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Pancreatitis, Chronic clinical trials

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NCT ID: NCT04403074 Recruiting - Clinical trials for Chronic Pancreatitis

Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis (EUS-CPN) for Chronic Pancreatitis

CPN
Start date: October 20, 2017
Phase:
Study type: Observational

Physicians need a tracking system for specific treatment modalities, and data to determine the impact of endoscopic ultrasound pain management for patients with chronic pancreatitis.

NCT ID: NCT04400357 Recruiting - Clinical trials for Pancreatic Adenocarcinoma

Robotic Versus Open Pancreaticoduodenectomy for Pancreatic and Periampullary Tumors

PORTAL
Start date: June 15, 2020
Phase: N/A
Study type: Interventional

This multicenter randomized trial aims to primarily assess and compare the functional recovery of patients who undergo open versus robotic pancreaticoduodenectomy for benign and malignant lesions of the head of the pancreas.

NCT ID: NCT04245189 Recruiting - Alcoholic Cirrhosis Clinical Trials

EUS Based Prevalence of Chronic Pancreatitis in Alcoholic Cirrhosis

Start date: February 1, 2021
Phase:
Study type: Observational

Alcohol is the common precipitating factor for both cirrhosis of liver as well as alcohol related chronic pancreatitis. However, in real life clinical setting, clinicians do not frequently see many cases of symptomatic pancreatitis in patients who present with features of cirrhosis of liver. On the contrary, in some patients presenting with alcohol related chronic pancreatitis, evidence of cirrhosis of liver is observed on imaging without other clinical features of cirrhosis.

NCT ID: NCT04131010 Recruiting - Clinical trials for Pancreatitis, Chronic

Digital Catheter Based Pancreatoscopy (SpyGlassDS) for the Management of Symptomatic Pancreatic Duct Stones in Selected Patients With Chronic Pancreatitis

Start date: May 31, 2019
Phase: N/A
Study type: Interventional

Investigation of the efficacy and safety of digital catheter-based pancreatoscopy (DCP) for the Treatment of symptomatic Stones of the pancreatic duct in selected patients with chronic calcifying pancreatitis (CCP)

NCT ID: NCT04095195 Recruiting - Lynch Syndrome Clinical Trials

Registry of Subjects at Risk of Pancreatic Cancer

IRFARPC
Start date: August 20, 2019
Phase:
Study type: Observational

IRFARPC is a multicenter national registry designed to study the diagnosis and predisposing factors of subjects with an inherited increased risk for pancreatic cancer.

NCT ID: NCT04021498 Recruiting - Clinical trials for Pancreatitis Relapsing

Simvastatin in the Prevention of Recurrent Pancreatitis

SIMBA-16
Start date: September 29, 2017
Phase: Phase 3
Study type: Interventional

Recurrent acute pancreatitis and recurrent relapses of inflammation in chronic pancreatitis are an important problem. In some cases, prevention of these acute flares of inflammation is not possible. Population-based studies and meta-analysis of randomized controlled trials suggest that statins may decrease the incidence of acute pancreatitis. SIMBA aims to investigate the effect of simvastatin on the incidence of new episodes of pancreatitis in recurrent acute pancreatitis and chronic pancreatitis. This is a non-profit, researcher-driven placebo-controlled multicenter (27 Spanish centers) randomized controlled trial

NCT ID: NCT03853447 Recruiting - Inflammation Clinical Trials

Fibro-inflammatory Progression From Acute to Chronic Pancreatitis

Start date: February 14, 2019
Phase:
Study type: Observational

Observational prospective study evaluating the developement of chronic pancreatitis based on imaging modalities as well as biochemical markers of inflammation, fibrosis and oxidative stress.

NCT ID: NCT03792048 Recruiting - Cholangiocarcinoma Clinical Trials

Magnetic Compressive Anastomosis for Biliojejunostomy and Pancreaticojejunostomy During Whipple's Procedure

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

Magnetic anastomosis has been attempted in biliary and intestinal reconstruction. Based on our initial experience, the investigators have successfully utilized magnetic anastomosis for biliojejunostomy and pancreaticojejunostomy during pancreaticoduodenectomy. The current study was to design a prospective and case-control study with utilization of magnetic compression anastomosis for pancreaticojejunostomy and biliojejunostomy in Whipple's procedure versus traditional hand-sewn technique on the postoperative morbidity, such as biliary/pancreatic fistula, hemorrhage, anastomotic stenosis, etc. In addition, the investigators are seeking to assess the safety and formation of the anastomosis by magnetic technique.

NCT ID: NCT03780946 Recruiting - Clinical trials for Pancreatic Neoplasms

Magnetic Compressive Technique for Pancreatic Intestinal Anastomosis

MCTPIA
Start date: February 1, 2019
Phase:
Study type: Observational [Patient Registry]

In recent five years, the investigators have successfully developed different types of magnets and utilized in biliojejunostomy, concomitant biliojejunostomy and pancreaticojejunostomy during Whipple. This study is designed as a prospective study by utilization of the bar-like magnets for pancreaticojejunostomy.

NCT ID: NCT03779139 Recruiting - Diabetes Mellitus Clinical Trials

Intra-Portal Alone Versus Intra- and Extra-Portal Transplantation of Pancreatic Islets After Total Pancreatectomy for Chronic Pancreatitis

iSite
Start date: August 1, 2019
Phase: N/A
Study type: Interventional

Randomized pilot trial of patients (n=30) undergoing Total Pancreatectomy and Islet AutoTransplant (TPIAT). Patients with islet harvest of greater than 5000 islet equivalents/kg body weight will be randomized to receive a portion of their islets into an omental pouch. For outcomes related to islet function, a group of normal volunteers (n=15) will be studied as a comparator group.