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Pancreaticoduodenectomy clinical trials

View clinical trials related to Pancreaticoduodenectomy.

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NCT ID: NCT06094465 Completed - Clinical trials for Pancreaticoduodenectomy

Learning Curve of Robotic Pancreatoduodenectomy

Start date: April 1, 2020
Phase:
Study type: Observational

A few reports were focused on the RPD learning curve for surgeons with extensive experience in LPD. Therefore, this study aimed to investigate the number of cases required for such surgeons to overcome the learning curve for RPD and to analyze the impact of different phases of the learning curve on perioperative outcomes.

NCT ID: NCT05680623 Completed - Clinical trials for Postoperative Complications

Clinical and Economic Validation of the ISGPS Definition of PPAP

ISGPS-PPAP
Start date: January 1, 2022
Phase:
Study type: Observational

This prospective validation study aims to investigate the incidence of PPAP after pancreaticoduodenectomy (PD) by applying the ISGPS definition and grading system, to demonstrate its clinical impact by examining associated postoperative outcomes, and to validate its applicability through an economic assessment.

NCT ID: NCT05581017 Completed - Clinical trials for Surgical Site Infection

Association of Cephalosporin Resistance and Surgical Site Infections in Patients Undergoing Pancreaticoduodenectomy

Start date: June 16, 2020
Phase:
Study type: Observational

Preoperative biliary drainage predisposes the bile to be contaminated with bacteria of the duodenum. These bacteria colonizing the bile are a potential source for surgical site infections after pancreaticoduodenectomy and many international guidelines recommend the use of cephalosporines as microbial prophylaxis before surgery. The aim of this study was to assess the incidence of bacteria in bile, their resistance profiles and association to surgical site infections in relation to timing of surgery after preoperative biliary drainage in order to better guide antibiotic use.

NCT ID: NCT05567094 Completed - Clinical trials for Pancreaticoduodenectomy

The Effect of Perioperative DEXamethasone on Postoperative Complications After PANcreaticoduodenectomy

PANDEX
Start date: October 8, 2022
Phase: Phase 4
Study type: Interventional

The primary objective of this clinical trial is evaluate the effect of dexamethasone on postoperative complications after pancreaticoduodenectomy.

NCT ID: NCT04989868 Completed - Clinical trials for Complication of Surgical Procedure

Effect of Trans-Nasal Afferent Loop Decompression on Post-Pancreaticoduodenectomy Pancreatic Fistula

Start date: August 6, 2021
Phase: N/A
Study type: Interventional

Postoperative pancreatic fistula (POPF) is a major complication and an important cause of mortality after pancreaticoduodenectomy (PD). Trans-nasal afferent loop decompression technique (TNALD) may reduce the rate of POPF based on our previous retrospective study. The aim of this open-label randomized controlled trial is to determine whether TNALD is a protective factor against the development of POPF after PD.

NCT ID: NCT04881734 Completed - Fatigue Clinical Trials

The Effect of Overtime Pancreaticoduodenectomy on the Short-term Prognosis of Patients(EOPSPP)

EOPSPP
Start date: January 1, 2021
Phase:
Study type: Observational

Surgeons sometimes need to work overtime or even stay up late to perform pancreaticoduodenectomy. Fatigue and sleep deprivation can result in an increased error rate at work. The effect of overtime work for pancreaticoduodenectomy on the prognosis of patients is unclear. The study explores the impact of overtime work for pancreaticoduodenectomy on the prognosis of patients. This was a single-center, retrospective study. The patients who underwent pancreaticoduodenectomy in Peking University People's Hospital between 2017 and 2019 were included. Patients were stratified by operative start time into the control group (surgery that started between 8:00 and 16:49) and the overtime group (surgery that started between 17:00 and 22:00) and compared intraoperative and postoperative parameters to clarify the impact of overtime surgery on the short-term prognosis of patients.

NCT ID: NCT04843670 Completed - Clinical trials for Pancreaticoduodenectomy

Isolated Pancreatic Loop With Modified Pancreaticojejunostomy

Start date: January 1, 2010
Phase:
Study type: Observational

The aim of the present study was to observe whether the modified pancreatico- jejunostomy (PJ ) technique with an isolated pancreatic loop would effectively reduce the POPF rate and overall morbidity after PD

NCT ID: NCT04053998 Completed - Clinical trials for Pancreatic Neoplasms

Benchmarking Outcomes in Pancreatic Surgery - WhippleBenchmarks.Org

Start date: August 9, 2019
Phase:
Study type: Observational

The WhippleBenchmark 2 Collaborative study aims at defining benchmark criteria for best achievable outcomes after pancreaticoduodenectomy with portal vein resection.

NCT ID: NCT03791450 Completed - Clinical trials for Pancreaticoduodenectomy

Investigation of Pancreaticoduodenectomy

Start date: March 1, 2019
Phase:
Study type: Observational

The investigators intend to conduct a multicentre, big-sample, retrospective study to analysis the surgery results of pancreaticoduodenectomy and compare the different suture technique.

NCT ID: NCT03699917 Completed - Clinical trials for Pancreaticoduodenectomy

Goal-directed Fluid Therapy on Complications After Pancreaticoduodenectomy

Start date: January 1, 2015
Phase:
Study type: Observational

Optimal fluid balance is critical to minimize anastomotic edema in patients undergoing pancreaticoduodenectomy. This study examined the effects of decreased fluid administration on rates of postoperative pancreatic leak and delayed gastric emptying.