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Pancreatic Surgery clinical trials

View clinical trials related to Pancreatic Surgery.

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NCT ID: NCT06381362 Recruiting - Pancreatic Surgery Clinical Trials

Italian Registry of Minimally Invasive Pancreatic Surgery

IGOMIPS
Start date: February 28, 2019
Phase:
Study type: Observational [Patient Registry]

Assess the prevalence of minimally invasive pancreatic surgery in the country and its outcomes

NCT ID: NCT05603702 Recruiting - Chronic Pain Clinical Trials

STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis

STTEPP
Start date: March 17, 2023
Phase: Phase 1
Study type: Interventional

The investigators propose to conduct a dose-escalation trial of an FDA-approved antiepileptic drug, lacosamide, added to opioid therapy in patients with chronic abdominal pain from chronic pancreatitis (CP). This pilot trial will test the feasibility of the study design and provide reassurance regarding the tolerability and safety of lacosamide used concomitantly with opioids in this patient population to reduce the condition known clinically as opioid-induced hyperalgesia (OIH).

NCT ID: NCT04196816 Completed - Pancreatic Cancer Clinical Trials

Surgery for Pancreatic Cancer With Oligo-Metastasis

SPaM
Start date: January 1, 2020
Phase:
Study type: Observational

Pancreatic cancer is increasing in incidence and will be the second leading cause of cancer-related deaths in 2030 in the West. Only 10 to 15% of patients are eligible for curative resection with long-term survival rarely exceeding 20% at 5 years. The management of metastatic or recurrent diseases can not, unfortunately, be recommended to date because of limited data available (INCA 2019). However, recent, low-strength publications have reported encouraging results on the long-term survival of stage IV or recurrent patients. The aim of the present retrospective cohort study is to analyze results of surgery/destruction of metastatic synchronous or metachronous disease or local recurrence in patients with stage IV pancreatic cancer

NCT ID: NCT03791346 Completed - Pancreatic Surgery Clinical Trials

Pancreatectomy for NET: External Evaluation of WHO 2017 Grading System

PanTEN
Start date: January 1, 1997
Phase:
Study type: Observational

Aim: The aim of this study was to investigate the clinicopathological factors and to evaluate the prognostic accuracy of the new World Health Organization (WHO) 2017 grading system in pancreatic neuroendocrine tumor (PanNET) patients. Methods: Data collected between 1997 and December 2017 were analyzed. Histological grading and staging was based on the WHO 2017 grading system. Outcome after surgery and predictors of overall survival (OS) and disease free survival (DFS) were evaluated.

NCT ID: NCT03462602 Not yet recruiting - Pancreatic Surgery Clinical Trials

Nasogastric Tube in Pancreatic Surgery

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

Introduction: The value of routine nasogastric tube (NGT) decompression after pancreatic surgeries is not yet established. Previous studies in the setting of abdominal surgery suggested that the use of NGT does not accomplish any of its intended goals. Methods/design: This is a prospective, randomized, controlled multicenter trial with two treatment arms. One group underwent pancreatic surgeries with routine NGT and was left in place after surgery until the patient passed flatus or stool. The other group underwent pancreatic surgeries without receiving NGT decompression, in which the NGT was removed at the end of surgery. Discussion: Routine NGT decompression after pancreatic surgeries does or does not appear to have its anticipated advantages would be discovered in this RCT.

NCT ID: NCT03000946 Completed - Pancreatic Surgery Clinical Trials

Prevention of Postoperative Pancreatic Fistula by Somatostatin

PREFIPS
Start date: May 15, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether somatostatin is more effective that octreotide in the prevention of post-pancreatectomy pancreatic fistula

NCT ID: NCT01059097 Completed - Pancreatic Cancer Clinical Trials

Effect of Surgeon Volume on Outcome of Pancreaticoduodenectomy

Start date: August 2001
Phase: N/A
Study type: Interventional

The independent impact of surgeon volume on outcome of patients undergoing pancreaticoduodenectomy in a high-volume Institution was assessed. A significant reduction of pancreatic fistula rate was found in the high-volume surgeon group in comparison with low-volume surgeon group. However, no difference between groups was found in mortality, major complications, and hospital stay.

NCT ID: NCT00671463 Withdrawn - Pancreatic Cancer Clinical Trials

Pancreatic Stent to Prevent Leak After Distal Pancreatectomy

LEAPS
Start date: April 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate an intervention to prevent complications after pancreas surgery. The goal is to determine if placing a stent into the pancreatic duct before surgery will decrease or prevent leaking from the pancreatic duct after surgery. Leaks are common after pancreas surgery and can result in serious problems and post-operative pain. The study will compare two groups. One group will have the stent before surgery, and the other group will have standard pancreas surgery, no endoscopy, and no stent.