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Clinical Trial Summary

The present study aims to evaluate the feasibility, safety and efficacy of EUS-FNI for MEN1-related pNETs


Clinical Trial Description

The management of multiple endocrine neoplasia type 1 (MEN1-1)-related pancreatic neuroendocrine tumors (pNETs) remains controversial. In general, surgical resection is currently the first-line therapy for MEN1-1-related pNETs. However, the surgical resection of pNETs is conditional for specific patients, and the incidence of postoperative adverse events is still high. Recently, several studies have demonstrated that endoscopic ultrasonography (EUS)-guided fine-needle injection (EUS-FNI) with ethanol or lauromacrogol may provide an alternative to surgical resection of pNETs. Nevertheless, their sample size was relatively small and conclusions were drawn based on short-term results. Therefore, a multicenter prospective study is being performed to further access the efficacy and safety of EUS-FNI for MEN1-1-related pNETs. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05554744
Study type Interventional
Source Guangxi Medical University
Contact Shanyu Qin, MD,Ph.D
Phone 86-771-5353725
Email qsy0511@163.com
Status Recruiting
Phase N/A
Start date June 18, 2015
Completion date December 2025

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