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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT05187416
Other study ID # KY20212175-C-1
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date February 1, 2022
Est. completion date October 1, 2022

Study information

Verified date October 2021
Source Xijing Hospital
Contact Kunlong Duan
Phone +8617795629885
Email 804868814@qq.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Pancreatic cancer is a gastrointestinal tumor with a high degree of malignancy. Currently, there are many first-line chemotherapy regimens in clinical practice, but the individual selection of chemotherapy regimens has not been unanimously recognized.This study is aimed at exploring the correlation between the two-dimensional shear wave elastography (2D - SWE) parameters and pancreatic cancer stromal elements proportion through an ultrasound scan for resectable pancreatic cancer cases and postoperative pathological specimen analysis. Then determine if the pancreatic cancer two-dimensional shear wave elastography can guide clinicians selecting chemotherapy scheme by predicting tumor stromal elements .These results are expected to provide an effective non-invasive diagnostic basis for individualized treatment of pancreatic cancer.


Recruitment information / eligibility

Status Recruiting
Enrollment 50
Est. completion date October 1, 2022
Est. primary completion date October 1, 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years to 100 Years
Eligibility Inclusion Criteria 1. Patients with resectable pancreatic cancer underwent ultrasound examination before surgery 2. Conventional ultrasound can clearly show pancreatic space-occupying lesions and the elastic measurements show good images 3. The patient agrees to receive ultrasound elasticity examination and signs informed consent 4. All patients had no history of radiotherapy or chemotherapy before ultrasound examination 5. All clinical case data and auxiliary examination data are complete and accessible. Exclusion Criteria 1. Ultrasound evaluation was not performed before ultrasound-guided needle biopsy 2. Conventional ultrasound could not clearly show pancreatic space-occupying lesions or poor elastic measurement images 3. Patients who refuse to accept examination or give up treatment 4. Patients receiving neoadjuvant chemotherapy or radiotherapy before ultrasound examination 5. Incomplete clinical data and auxiliary examination data.

Study Design


Related Conditions & MeSH terms


Intervention

Diagnostic Test:
two-dimensional shear wave elastography
Preoperative ultrasound elastography examination

Locations

Country Name City State
China Xijing Hospital Xi'an Shaanxi

Sponsors (1)

Lead Sponsor Collaborator
Xijing Hospital

Country where clinical trial is conducted

China, 

Outcome

Type Measure Description Time frame Safety issue
Primary Elastic modulus measured by Ultrasonic shear wave and tumor stromal component assessed by pathological analysis in pancreatic cancer Baseline (Preoperative ultrasound elastography examination)
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