Pancreatic Neoplasm Clinical Trial
Official title:
Prospective Evaluation of the Significance of the Pro-core® Needle in Differential Diagnosis of Tumorous and Inflammatory Processes
The study is designed to evaluate the diagnostic accuracy of a new designed endoscopic ultrasonography (EUS) Core biopsy aspiration needle in comparison to a conventional EUS aspiration needle in GI-tumors.
Endoscopic ultrasound is an established examination method for tumors of the gastrointestinal
tract and the pancreas. Since imaging by itself is limited in differential diagnosis of
tumors, EUS guided fine needle aspiration is seen as a valid complementary method. Since
fine-needle aspiration (FNA) is mainly based on cytological diagnostics, this method is
limited also because of lacking supplementary immune- histochemical diagnostics. Here, the
obtainment of little histologically evaluable tissue samples (punched barrels) would be of
benefit.
A new punch needle device called Pro-core needle (Cook)(22 / 19 gauges) offers the
possibility of increasing numbers of valid extractions of histologically evaluable tissues
due to a better targeted precision and maneuverability in comparison to other devices of that
kind (tru-cut needles, e.g.). A little notch at the pinpoint allows the obtainment of little
tissue samples, that will be kept within the device by aspiration.
This study compares the obtainment of tissue by Proc-core needle and conventional aspiration
punction systems.
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