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Pancreatic Disease clinical trials

View clinical trials related to Pancreatic Disease.

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NCT ID: NCT05832047 Recruiting - Pancreatic Disease Clinical Trials

Aggressive Hydration With Lactated Ringer's Solution Versus Plasma Solution for the Prevention of Post ERCP (Endoscopic Retrograde Cholangiopancreatography) Pancreatitis

Start date: June 19, 2023
Phase: Phase 4
Study type: Interventional

In the existing Aggressive hydration comparison study related to the prevention of post-ERCP pancreatitis (PEP), research bias may occur due to the lack of blinding between fluids, so in this study, the investigators will conduct a multicenter randomized comparative study in which the comparative fluids are double-blinded to observe differences between fluids in the preventive effect of pancreatitis that occurs after ERCP (endoscopic retrograde cholangiopancreatography). A total of 844 patients scheduled for ERCP will be enrolled in this clinical trial and randomly assigned to the lactated Ringer's solution or to the Plasma solution in a 1:1 ratio. Eligible patients will receive study drug or control drug for up to 24 hours before and after ERCP implementation.

NCT ID: NCT05792267 Recruiting - Pancreatic Disease Clinical Trials

Clinical Research on a Novel Deep-learning Based System in Pancreatic Endoscopic Ultrasound Scanning

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to develop and verify the auxiliary role of the artificial intelligence system in pancreatic ultrasound endoscopic scanning.The main questions it aims to answer are as follows: 1.The comparison of the image recognition accuracy between the artificial intelligence system and the ultrasound endoscopist; 2. Whether the artificial intelligence system can improve the efficiency of the pancreatic scanning for the ultrasound endoscopist. Participants will undergo pancreatic EUS with or without the assistance of the artificial intelligence system.

NCT ID: NCT05743972 Not yet recruiting - Pancreatic Disease Clinical Trials

Contrast-Enhanced Ultrasound vs Conventional US-guided Percutaneous Needle Biopsy for Pancreatic Diseases: Prospective Multicenter Randomized Controlled Trial

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

According to previous studies, contrast-enhanced ultrasound (CEUS) -guided Core Biopsy(GB) could improve the diagnosis of biopsy in liver and other superficial mass compared to conventional US-GB. The purpose of this randomized trial is to estimate whether CEUS-GB achieve excellent diagnostic value to conventional US-GB in percutaneous biopsy for pancreatic diseases.

NCT ID: NCT05709197 Recruiting - Pancreatic Cancer Clinical Trials

The Effectiveness of Adding Braun Anastomosis to Standard Child Reconstruction After Pancreatoduodenectomy

REMBRANDT
Start date: April 17, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial (REMBRANDT) is to evaluate the effectiveness of adding an extra connection (i.e. 'Braun anastomosis') after standard reconstruction in pancreatic head resection in reducing the incidence of delayed gastric emptying.

NCT ID: NCT05515705 Recruiting - Pancreatic Disease Clinical Trials

First-in-human Navigation Endoscopic Ultrasound (EUS) System Clinical Study

APEUS-Nav1
Start date: January 10, 2023
Phase: N/A
Study type: Interventional

The implementation of Echo-endoscopy (or EUS for: Endoscopic UltraSound) is limited by the difficulty of obtaining quality EUS procedures, since the accuracy of the method relies on the endoscopist's abilities. Indeed, both cognitive and technical skills are required for endoscopic manipulation and image interpretation, as well as a thorough knowledge of intra-abdominal anatomy. The "EUS-GPS" system aims to assist the operator in understanding the orientation and location of the probe tip within the patient. For that, a Global Positioning System (GPS) for EUS procedures is intraoperatively provided, using a 3D-based model based on recorded preoperative data. In this clinical investigation, the EUS GPS system is intended to help EUS operators to correctly navigate towards the pancreatic gland, perform a comprehensive assessment of the area of interest, and aid in the detection and identification of lesions.

NCT ID: NCT05474417 Recruiting - Kidney Diseases Clinical Trials

The Effects of the CF Carrier State on the Kidneys and Pancreas

Start date: December 20, 2021
Phase:
Study type: Observational

The overarching hypothesis is that CF carriers are at increased risk for developing most of the extrapulmonary conditions associated with CF compared to the general population. Specifically, it is hypothesized that this pilot data will detect subclinical evidence of pancreatic and kidney disorders among CF carriers. This will be determined by bringing CF carriers and controls to the CRU for one visit where they will answer survey questions and undergo laboratory testing. Additionally, they will collect urine and stool samples at home that will be sent to outside laboratories for testing.

NCT ID: NCT05457101 Recruiting - Clinical trials for Artificial Intelligence

Validation of an AI-based Biliopancreatic EUS Navigation System for Real-time Quality Improvement: A Prospective, Single-center, Randomized Controlled Trial

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

Endoscopic ultrasonography (EUS) is a key procedure for diagnosing biliopancreatic diseases. However, the performance among EUS endoscopists varies greatly and leads to blind areas during operation, which impaired the health outcome of patients. We previously developed an artificial intelligence (AI) device that accurately identifies EUS standard stations and significantly reduces the difficulty of ultrasound image interpretation. In this study, we updated the device (named EUS-IREAD) and assessed its performance in improving the quality of EUS examination in a single-center randomized controlled trial.

NCT ID: NCT05429203 Recruiting - Clinical trials for Pancreatic Neoplasms

Comparison of Duodenoscope With Single-use Distal Cover and the Conventional Reusable Duodenoscope

Start date: October 25, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to compare the success rates of procedure success and complication rates in patients undergoing Endoscopic retrograde cholangiopancreatography (ERCP) using two types of currently available endoscopes. These are (1) duodenoscope with a Single-use distal cover or (2) a conventional reusable duodenoscope.

NCT ID: NCT05392452 Completed - Clinical trials for Diabetes Mellitus, Type 2

Fully Closed-Loop Insulin Delivery in Abdominal Surgery (CLAB)

CLAB
Start date: August 9, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to assess the efficacy, safety and usability of perioperative fully-automated closed-loop insulin delivery versus standard insulin therapy in patients with diabetes other than type 1 diabetes undergoing elective major abdominal surgery.

NCT ID: NCT05253859 Active, not recruiting - Cystic Fibrosis Clinical Trials

CFTR Modulators and Gastrointestinal Complications

CFTR-MAGIC
Start date: October 1, 2021
Phase:
Study type: Observational

To elucidate the similarities and distinctions in non-pulmonary manifestations of cystic fibrosis (CF) including distal intestinal obstruction syndrome (DIOS) incidence and pancreatic enzyme replacement therapy (PERT) use between US and UK CF populations in a parallel study using data from the UK and US CF registries. To assess how CFTR modulators impacted upon recorded PERT use and incidence of DIOS.