Role of Patient Selection for Pancreatic Resections

Pancreas Disease Clinical Trial

— PatSelPanc  

Official title:

Importance of Patient Characteristics in Identifying and Selecting Patients Suitable for Pancreatic Resection

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06390891
• Other study ID #: PatSelPanc
• Status: Completed
• Start date: January 1, 2010
• Est. completion date: December 31, 2018

Study information

• Verified date: April 2024
• Source: Medizinische Hochschule Brandenburg Theodor Fontane
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Pancreatic surgery is complicated and risky, especially for pancreatic cancer. It's been noticed that having these surgeries done at specialized centers can lead to better outcomes and survival rates. However, factors like patient selection and hospital conditions also play an important role. Some studies show that more surgeries done at a hospital might not always mean better results, as the type of patients and procedures can vary. To understand this better, the present study compared outcomes and patient characteristics between high-volume pancreatic centers and others.

Description:

The study utilized German nationwide administrative data (diagnosis-related group statistics) spanning from 2010 to 2018. Persons who underwent pancreatic resections during this period were included, with exclusions for certain criteria like underage and type of procedure. Various factors including patient demographics, diagnoses, procedures, and comorbidities were analyzed to assess in-hospital mortality rates. High-volume pancreatic centers (HVPCs) were identified as those performing at least 50 procedures annually. Statistical analyses included comparing crude and adjusted mortality rates and assessing patient characteristics between HVPCs and non-HVPCs. Models were adjusted for multiple variables, and methods like the Cochran-Armitage trend test and mixed models were employed. Additionally, the study investigated how differences in patient characteristics between HVPCs and non-HVPCs affected mortality rates.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 86073
• Est. completion date: December 31, 2018
• Est. primary completion date: December 31, 2018
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• partial or total pancreatic resections between 2010 and 2018

Exclusion Criteria:

• childhood (<18 years)

• subjects with a pancreatic transplantation procedure

• missing information on age or gender

Related Conditions & MeSH terms

• Pancreas Disease
• Pancreatic Diseases

Intervention

Other:
• Persons with pancreatic resection in a hospital with at least 50 pancreatic resections annually (observational),
Persons that have undergone a pancreatic resection at a hospital with at least 50 pancreatic resections annually (observational)
• Persons with pancreatic resection in a hospital not performing at least 50 pancreatic resections annually (observational),
Persons that have undergone a pancreatic resection at a hospital with not at least 50 pancreatic resections annually (observational)

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Medizinische Hochschule Brandenburg Theodor Fontane

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	In-hospital mortality	Death	30 days