Muscle Stretching - the Potential Role of Endogenous Pain Inhibitory Modulation on Stretch Tolerance

Pain Threshold Clinical Trial

Official title:

Muscle Stretching - the Potential Role of Endogenous Pain Inhibitory Modulation on Stretch Tolerance

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03713788
• Other study ID #: UniversityCND
• Status: Completed
• Phase: N/A
• Start date: May 1, 2016
• Est. completion date: November 30, 2016

Study information

• Verified date: October 2018
• Source: University College of Northern Denmark
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study investigates the influence of a remote, painful stimulus on stretch tolerance. Half of the participants will receive a conditioning painful stimulus following static stretching while the other half will rest quietly.

Description:

The effect of stretching on joint range of motion is primarily related to changes in the tolerance to stretch, but the mechanisms underlying this change are still largely unknown.

The nervous system has an inbuilt ability to modulate the perceived magnitude of afferent noxious stimuli via supraspinally mediated endogenous pain inhibition or facilitation and by engaging endogenous mechanisms pain tolerance in healthy individuals is known to increase. Thus increasing the tolerance to pain could potentially increase range of motion following stretching.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 34
• Est. completion date: November 30, 2016
• Est. primary completion date: November 30, 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 45 Years

Eligibility

Inclusion Criteria:

• Eligibility for participation included the absence of any pain or other conditions that might affect the somatosensory system.

Exclusion Criteria:

• Substance abuse,

• History of neurological or mental disabilities

• Lack of ability to comply with instructions

• Delayed onset of muscle soreness.

Related Conditions & MeSH terms

• Muscle Stretching Exercises
• Pain Threshold

Intervention

Other:
• Cold pressor test
Participants placed their non-dominant hand into cold water for 2 minutes

Locations

Country	Name	City	State
Denmark	University College of Northern Denmark	Aalborg

Sponsors (2)

Lead Sponsor	Collaborator
University College of Northern Denmark	Aalborg University

Country where clinical trial is conducted

Denmark, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Knee extension range of motion	Passively induced knee extension range of motion was measured usind the Biodex system 4 pro isokinetic dynomometer	Passive knee extension range of motion was measured at baseline
Primary	Change in knee extension range of motion between baseline and post stretch.	Changes in passively induced knee extension range of motion was measured using the Biodex system 4 pro isokinetic dynomometer	Changes in passive knee extension range of motion were measured 5 minutes after baseline measures following stretching
Primary	Changes in knee extension range of motion between post stretch and post pain.	Changes in passively induced knee extension range of motion was measured using the Biodex system 4 pro isokinetic dynomometer	Changes in passive knee extension range of motion were measured 5 minutes after post stretch measures following intervention.
Secondary	Surface electromyography measures of muscle activity	Muscle activity during the passive knee extension motion were measured using SEMG.	Muscle activity during the passive knee extension motion was measured at baseline
Secondary	Changes in surface electromyography measures of muscle activity between baseline and post stretch measures.	Changes in muscle activity during the passive knee extension motion were measured using SEMG.	Changes in muscle activity during the passive knee extension motion were measured 5 minutes after baseline measures following stretching.
Secondary	Changes in surface electromyography measures of muscle activity between post stretch and post pain measures.	Changes in muscle activity during the passive knee extension motion were measured using SEMG.	Changes in muscle activity during the passive knee extension motion were measured 5 minutes after post stretch measures following intervention.
Secondary	Passive resistive torque using the Biodes system 4 pro.	Passive resistive torque during the passive knee extension motion was measured using the Biodex system 4 pro isokinetic dynamometer.	Passive resistive torque during the passive knee extension motion was measured at baseline.
Secondary	Changes in passive resistive torque measured using the Biodex system 4 pro between baseline and post stretch measures.	Changes in passive resistive torque during the passive knee extension motion was measured using the Biodex system 4 pro isokinetic dynamometer.	Changes in passive resistive torque during the passive knee extension motion was measured 5 minutes after baseline measures following stretching.
Secondary	Changes in passive resistive torque measured using the Biodex system 4 pro between post stretch and post pain measures.	Changes in Passive resistive torque during the passive knee extension motion was measured using the Biodex system 4 pro isokinetic dynamometer.	Passive resistive torque during the passive knee extension motion was measured 5 minutes after post stretch measures following intervention.