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Pain Relief clinical trials

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NCT ID: NCT04586712 Completed - Recovery Clinical Trials

Efficacy of a Controlled Short-term Trial of Cannabidiol (CBD) Ingestion on Reducing Symptomatic Response and Facilitating Recovery After Induced Muscle Injury

Start date: March 1, 2021
Phase: Phase 2
Study type: Interventional

The study aims to determine the efficacy of a controlled short-term trial of CBD ingestion for reducing symptomatic response and facilitating recovery following induced muscle injury. A double-blind, randomized, three-arm study design will be used and participants will be randomly assigned to either a high dose (n=15), low dose (n=15), or vehicle control group (n=15). The clinical outcomes include measures of muscular pain and disability along with measures of pain-related fear and anxiety.

NCT ID: NCT04473508 Completed - Spine Surgery Clinical Trials

Erectus Nerve Block for Lumbar Spine Surgery

EFABE
Start date: November 27, 2019
Phase: Phase 3
Study type: Interventional

: Spine surgery induced severe postoperative pain. Several techniques as intravenous multimodal analgesia have been proposed to reduce pain relief and morphine rescue over the first postoperative days. Regional anesthesia using the erectus nerve block is a simple infiltration across lamina of the vertebra: Ultrasound-guided posterior ramus of spinal nerve block for anesthesia and analgesia in lumbar spinal surgery This study compared erector nerve block with local anesthetic vs placebo to reduce pain and morphine rescue after lumbar spine surgery. The investigators hypothesized that eructor nerve block induced a large block from L1 to L5 that induced posterior nerve roots block anesthesia. This block reduced pain after surgery.

NCT ID: NCT03733015 Completed - Pain Relief Clinical Trials

Daily Sessions of rTMS to the Left DLPFC Modulate the Pain Thresholds and CPM

Start date: October 10, 2018
Phase: N/A
Study type: Interventional

The main purpose of the study is to assess whether repeated sessions of repetitive trancranial magnetic stimulation (rTMS) applied on left dorsolateral prefrontal cortex main boost the pain thresholds.

NCT ID: NCT03263884 Completed - Pain Relief Clinical Trials

Repetitive Transcranial Magnetic Stimulation and the Development of Ongoing Muscle Pain

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

The main purpose of the study is to assess the mechanisms of repeated sessions of repetitive trancranial magnetic stimulation (rTMS) applied on left dorsolateral prefrontal cortex on the development of pain in a prolonged muscle pain model.

NCT ID: NCT02969902 Completed - Pain Relief Clinical Trials

Buzzy Distraction During Venipuncture

Start date: November 2014
Phase: N/A
Study type: Interventional

Venipuncture is one of the most common iatrogenic painful and stressful procedures performed on children. Interventions aimed at reducing the distress related to this experience are widely and strongly recommended. Pain and anxiety management is even more essential because it may modify children's memory for procedural pain and the subsequent acceptance of later health care painful interventions. Distraction is the most studied psychological technique to relieve venipuncture related pain and distress, with a strong evidence supporting its efficacy in children and adolescents. In recent years several studies showed the effectiveness of a specific tool named Buzzy® (MMJ Labs, Atlanta GA, USA), in relieving pain and distress in children. Buzzy combines distraction and physical analgesia (vibration and cold) and it was positively tested during venipuncture, intravenous cannulation and painful injections in children. Even though its efficacy it's well established, most of the published trials did not compare Buzzy with other interventions, so that little data are available about its usefulness compared with other distractions techniques. Hand-held computers are reusable tools, which offer a technological-based active distraction. There is evidence supporting their used during painful procedures such as venipuncture and a recent published study showed that hand-held computer distraction was as effective as nurse-led passive distraction techniques in children. The aim of this study is to compare the effectiveness of Buzzy versus hand-held computer in pain relief during venipuncture.

NCT ID: NCT02943135 Completed - Pain Relief Clinical Trials

Lidocaine In-situ Gel Before Intrauterine Device Insertion

Start date: October 1, 2017
Phase: Phase 3
Study type: Interventional

Intrauterine device can cause pain and discomfort in several ways: Use of the tenaculum to grasp the cervix and straighten the uterus for proper insertion; trans-cervical actions including measuring uterine depth, inserting the insertion tube, and removing the tube; and placement of the device in the uterus.

NCT ID: NCT02905058 Completed - Pain Relief Clinical Trials

Efficacy of Ketoprofen Before Intrauterine Device Insertion

Start date: October 2016
Phase: Phase 3
Study type: Interventional

IUD can cause pain and discomfort in several ways: Use of the tenaculum to grasp the cervix and straighten the uterus for proper insertion; trans-cervical actions including measuring uterine depth, inserting the IUD insertion tube, and removing the tube; and placement of the device in the uterus.

NCT ID: NCT02905045 Completed - Pain Relief Clinical Trials

Efficacy of Ketoprofen Before Hysterosalpingography

Start date: October 2016
Phase: Phase 3
Study type: Interventional

hysterosalpingography can cause pain and discomfort in several ways: Use of the tenaculum to grasp the cervix and straighten the uterus for proper insertion; trans-cervical actions including measuring uterine depth, inserting the cannula; and injection of the dye

NCT ID: NCT02901561 Completed - Pain Relief Clinical Trials

Comparison Between 2 Doses of Misoprostol Before Intrauterine Device

Start date: September 2016
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of the investigators' study was to evaluate whether misoprostol will improve pain scores .

NCT ID: NCT02710305 Completed - Pain Relief Clinical Trials

Oral Hyoscine Butyl Bromide With Cervical Lidocaine Cream in Reducing Pain During Hysterosalpingography

HBTB
Start date: April 2016
Phase: Phase 2
Study type: Interventional

hysterosalpingography is a diagnosis procedure in the evaluation of infertile women and considered to be the traditional and the gold standard in the assessment of the patency of the fallopian tubes. The major disadvantage of hysterosalpingography is pain. In a study reported the patients complained of moderate to severe pain during the procedure. It is reported that some patients undergoing hysterosalpingography was more stressful and anxiety and effect on pain scores.