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Pain Relief clinical trials

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NCT ID: NCT06456177 Recruiting - Pain Relief Clinical Trials

Nociception Monitoring During Epidural Analgesia

Start date: June 30, 2021
Phase:
Study type: Observational

Introduction and aim: Nociception monitors have been used to assess pain management in anesthetized patients. The investigators set out to evaluate whether Nociception Level (NOL) monitor (PMD-200 monitor with NOL technology , (Medasense Biometrics Ltd. Ramat Gan, Israel) yields reliable readings during labor, and whether the derived NOL index will be associated with Visual analogue scale (VAS) subjective level of pain before and after the onset of epidural analgesia. Methods: Following approval by the intuitional review board No 0056-21-CMC, thirty parturients scheduled for epidural analgesia due to labor pains will be included in this prospective study, after informed consent for participation in the study will be obtained. NOL monitoring device will be connected to the subject finger. Epidural analgesia will be performed as per institutional standards. Data of VAS and NOL index will be collected once a minute. The association between VAS and NOL before and after the onset of adequate analgesia will be evaluated.

NCT ID: NCT04781777 Not yet recruiting - Pain Relief Clinical Trials

Effect of Ultrasonographic Guided Insulin Injection With Dexamethasone and Local Anesthetic Mixture in Diabetic Patients With Mild to Moderate Carpal Tunnel .

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

Insulin as an adjuvant to local anesthetic and cortisone to decrease pain recurrence

NCT ID: NCT04656821 Recruiting - Clinical trials for Erector Spinae Plane Block

Erector Spinae Block Versus Thoracic Paravertebral Block for Acute Thoracic Herpes Zoster

Start date: December 5, 2020
Phase: Phase 4
Study type: Interventional

The aim of this research is to study and compare the efficacy and safety of single injection erector spinae plane block and thoracic paravertebral block in prevention of post herpetic neuralgia in patients with acute thoracic herpes zoster.

NCT ID: NCT04586712 Completed - Recovery Clinical Trials

Efficacy of a Controlled Short-term Trial of Cannabidiol (CBD) Ingestion on Reducing Symptomatic Response and Facilitating Recovery After Induced Muscle Injury

Start date: March 1, 2021
Phase: Phase 2
Study type: Interventional

The study aims to determine the efficacy of a controlled short-term trial of CBD ingestion for reducing symptomatic response and facilitating recovery following induced muscle injury. A double-blind, randomized, three-arm study design will be used and participants will be randomly assigned to either a high dose (n=15), low dose (n=15), or vehicle control group (n=15). The clinical outcomes include measures of muscular pain and disability along with measures of pain-related fear and anxiety.

NCT ID: NCT04473508 Completed - Spine Surgery Clinical Trials

Erectus Nerve Block for Lumbar Spine Surgery

EFABE
Start date: November 27, 2019
Phase: Phase 3
Study type: Interventional

: Spine surgery induced severe postoperative pain. Several techniques as intravenous multimodal analgesia have been proposed to reduce pain relief and morphine rescue over the first postoperative days. Regional anesthesia using the erectus nerve block is a simple infiltration across lamina of the vertebra: Ultrasound-guided posterior ramus of spinal nerve block for anesthesia and analgesia in lumbar spinal surgery This study compared erector nerve block with local anesthetic vs placebo to reduce pain and morphine rescue after lumbar spine surgery. The investigators hypothesized that eructor nerve block induced a large block from L1 to L5 that induced posterior nerve roots block anesthesia. This block reduced pain after surgery.

NCT ID: NCT03733015 Completed - Pain Relief Clinical Trials

Daily Sessions of rTMS to the Left DLPFC Modulate the Pain Thresholds and CPM

Start date: October 10, 2018
Phase: N/A
Study type: Interventional

The main purpose of the study is to assess whether repeated sessions of repetitive trancranial magnetic stimulation (rTMS) applied on left dorsolateral prefrontal cortex main boost the pain thresholds.

NCT ID: NCT03263884 Completed - Pain Relief Clinical Trials

Repetitive Transcranial Magnetic Stimulation and the Development of Ongoing Muscle Pain

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

The main purpose of the study is to assess the mechanisms of repeated sessions of repetitive trancranial magnetic stimulation (rTMS) applied on left dorsolateral prefrontal cortex on the development of pain in a prolonged muscle pain model.

NCT ID: NCT03184649 Enrolling by invitation - Pain Relief Clinical Trials

Ibuprofen, Paracetamol Versus Placebo on Pain During Local Anesthetic Injection (RCT)

Start date: May 1, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

The Effect of Ibuprofen, Paracetamol versus Placebo on Pain during Local Anesthetic Injection and Following Dental Extraction in Primary Molars: A Randomized clinical trial

NCT ID: NCT02969902 Completed - Pain Relief Clinical Trials

Buzzy Distraction During Venipuncture

Start date: November 2014
Phase: N/A
Study type: Interventional

Venipuncture is one of the most common iatrogenic painful and stressful procedures performed on children. Interventions aimed at reducing the distress related to this experience are widely and strongly recommended. Pain and anxiety management is even more essential because it may modify children's memory for procedural pain and the subsequent acceptance of later health care painful interventions. Distraction is the most studied psychological technique to relieve venipuncture related pain and distress, with a strong evidence supporting its efficacy in children and adolescents. In recent years several studies showed the effectiveness of a specific tool named Buzzy® (MMJ Labs, Atlanta GA, USA), in relieving pain and distress in children. Buzzy combines distraction and physical analgesia (vibration and cold) and it was positively tested during venipuncture, intravenous cannulation and painful injections in children. Even though its efficacy it's well established, most of the published trials did not compare Buzzy with other interventions, so that little data are available about its usefulness compared with other distractions techniques. Hand-held computers are reusable tools, which offer a technological-based active distraction. There is evidence supporting their used during painful procedures such as venipuncture and a recent published study showed that hand-held computer distraction was as effective as nurse-led passive distraction techniques in children. The aim of this study is to compare the effectiveness of Buzzy versus hand-held computer in pain relief during venipuncture.

NCT ID: NCT02943135 Completed - Pain Relief Clinical Trials

Lidocaine In-situ Gel Before Intrauterine Device Insertion

Start date: October 1, 2017
Phase: Phase 3
Study type: Interventional

Intrauterine device can cause pain and discomfort in several ways: Use of the tenaculum to grasp the cervix and straighten the uterus for proper insertion; trans-cervical actions including measuring uterine depth, inserting the insertion tube, and removing the tube; and placement of the device in the uterus.