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Pain, Procedural clinical trials

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NCT ID: NCT04718116 Recruiting - Surgery Clinical Trials

Tapentadol Versus Tramadol Analgesia Post Cardiac Surgery

vasso-annie
Start date: November 1, 2022
Phase: N/A
Study type: Interventional

The aim of this randomized one-blinded study will be to evaluate the efficacy and tolerability of two different oral doses of tapentadol and compare it to tramadol (an opioid commonly used to treat post-surgical pain) in cardiac surgery patients

NCT ID: NCT04573088 Recruiting - Clinical trials for Colorectal Neoplasms

Acceptance-based Intervention at Colorectal Cancer Patients

ABICOL
Start date: June 22, 2020
Phase: N/A
Study type: Interventional

Taking into account the unavoidable effect of a major oncologic surgery commonly required for colorectal cancer patients and the recognized psychological and functional sequelae of the surgical treatment on their status, we will evaluate the influence of a psychological intervention, known as acceptance-based intervention, offered to those patients at the preoperative setting. Reduction of anxiety and assessmemt of indices of post-intervention psychological and functional recovery will be the primary goals of the study.

NCT ID: NCT04571879 Recruiting - Procedural Pain Clinical Trials

Nebulized Lidocaine and Intranasal Midazolam for NGT Insertion in Children

Start date: August 25, 2021
Phase: Phase 3
Study type: Interventional

Nasogastric tube (NGT) is a commonly performed procedure in the Emergency Department. Although it is not a major procedure, it is usually associated with a bad experience and cause discomfort and pain in kids. This randomized controlled double-blinded double-dummy trial aims to investigate the efficacy of local topical anesthetic and/or anxiolysis for pain/anxiety related to NGT insertion. Eligible patients are children with gastroenteritis aged 6 months to 5 years requiring NGT rehydration. The intervention are 3 arms of nebulized lidocaine with midazolam compared to nebulized midazolam alone or placebo. The primary outcome is procedure-related pain assessment using the Face, Legs, Activity, Cry, and Consolability (FLACC) scale during final NGT insertion attempt.

NCT ID: NCT04479735 Recruiting - Pain, Procedural Clinical Trials

Virtual Reality Goggle Utilization for Venipuncture Distraction

Start date: July 16, 2021
Phase: N/A
Study type: Interventional

This is a randomized non-blinded trial evaluating the effect of virtual reality goggles on perceived pain and anxiety scores during venipuncture on hospitalized children ages 5-21. We will randomized patients to either standard of care (including Lidocaine 2.5%/Prilocaine 2.5% cream as a topical anesthetic 60-240 minutes prior to venipuncture) or standard of care plus virtual reality goggles.

NCT ID: NCT04305743 Recruiting - Clinical trials for Urinary Bladder, Overactive

Post-procedural Pain Associated With 5 Versus 20 Intravesical Injections of Onabotulinumtoxin A

Start date: October 9, 2019
Phase: Phase 4
Study type: Interventional

Currently, in clinical practice there has been no standardization in the number of injections a single dose of intradetrusor onabotulinumtoxin A is administered in. Given the increasing use of this treatment modality, the aim of this study is to compare outcomes for patients given a 100 unit dose of onabotulinumtoxin A split into 5 as compared to 20 injections for the treatment of overactive bladder or urgency urinary incontinence refractory to medical treatment.

NCT ID: NCT04212208 Recruiting - Pain, Procedural Clinical Trials

Pain Assessment in the Perioperative Area

EMLA
Start date: February 1, 2019
Phase: N/A
Study type: Interventional

This study is mainly focusing on reducing the pain scores during IV cannulation in pediatric population in the preoperative period. Applying EMLA cream is a well-known fact world wide. we would like to study the effect of ultrasound waves in the penetration of the given drung into the skin so that we could achieve the effect of the drug quickly.

NCT ID: NCT04041635 Recruiting - Premature Clinical Trials

Reduction of Visual and Auditory Stimuli to Reduce Pain During Venipuncture in Premature Infants.

VENOPUNCIPREM
Start date: July 1, 2019
Phase: N/A
Study type: Interventional

The aim of the study is: To evaluate the efficacy of the reduction of visual and auditory stimuli on pain during venipuncture in premature newborns of 32-36 weeks of gestation.

NCT ID: NCT03740607 Recruiting - Procedural Pain Clinical Trials

Virtual Reality for Alleviation of Peripheral IV Placement-Associated Discomfort

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

Immersive virtual reality (iVR) has been used successfully to manage pain with distraction. It is a non-invasive treatment modality unassociated with worrisome well-known side effects typically seen when opioids and NSAIDS are used, and has previously been used safely in place of analgesia during dressing changes and burn care. This study investigates whether iVR can be useful as a stand-alone option to manage the pain associated with placement of peripheral intravenous (PIV) catheters in adults.

NCT ID: NCT02419651 Recruiting - Pain, Procedural Clinical Trials

Tramadol Versus Diclofenac for Reducing Pain Before Outpatient Hysteroscopy

Start date: April 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the effectiveness of Tramadol and diclofenac in reducing pain during outpatient hysteroscopy. Women undergoing outpatient hysteroscopy in Cairo university will be divided into 3 groups, the first group will receive Tramadol 100 mg 1 hour before the procedure, the second group will receive diclofenac 100mg 1 hour before the procedure and the third will receive a placebo. Pain will be assessed by a visual analogue scale