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Clinical Trial Summary

This proposed pilot study will investigate the safety and initial effectiveness of focused ultrasound lesioning of the contralateral mesencephalon for severe, opioid-resistant pain associated with head and neck cancer


Clinical Trial Description

This pilot study is designed as a prospective, open-label clinical trial of stereotactic FUS mesencephalotomy in 6 subjects with treatment-refractory pain from head and neck cancer. Primary safety assessments will be made throughout the study period of 6 months following the procedure. Primary efficacy outcome is determined by comparing the difference in baseline NPRS to 3 months post treatment. All subjects receiving treatment will be followed for the six month study period. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03894553
Study type Interventional
Source University of Virginia
Contact Matthew Patterson
Phone 434-243-7336
Email mwp5f@virginia.edu
Status Recruiting
Phase N/A
Start date June 22, 2020
Completion date August 31, 2024

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