Cancer of Head and Neck Clinical Trial
Official title:
Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy for Pain Palliation in Head & Neck Cancer
This proposed pilot study will investigate the safety and initial effectiveness of focused ultrasound lesioning of the contralateral mesencephalon for severe, opioid-resistant pain associated with head and neck cancer
This pilot study is designed as a prospective, open-label clinical trial of stereotactic FUS mesencephalotomy in 6 subjects with treatment-refractory pain from head and neck cancer. Primary safety assessments will be made throughout the study period of 6 months following the procedure. Primary efficacy outcome is determined by comparing the difference in baseline NPRS to 3 months post treatment. All subjects receiving treatment will be followed for the six month study period. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Withdrawn |
NCT05331131 -
Efficacy of Ketamine Mouthwash in the Management of Oral and Pharyngeal Toxicity Associated With Head and Neck Chemoradiotherapy: A Phase 2, Simon 2-stage Trial
|
Phase 2 | |
Completed |
NCT05269342 -
Nurse-led Exercise Improves Shoulder Pain, Shoulder Disability, and Quality of Life in Head and Neck Cancer
|
N/A | |
Completed |
NCT03574870 -
Wearable Sensor for Biometrics During Locoregional Therapy for Head and Neck Cancer
|
N/A | |
Recruiting |
NCT04804852 -
Assessment of the Prevalence of Sarcopenia by CT Scan in Patients Diagnosed With Head & Neck Cancer
|
||
Active, not recruiting |
NCT04617678 -
A Comprehensive Approach to Head and Neck Cancer Prehabilitation
|
N/A | |
Completed |
NCT03419741 -
Brain Stimulation For Cancer Smokers
|
N/A | |
Recruiting |
NCT02528955 -
De-Intensification Radiotherapy Postoperative Head Neck
|
Phase 2 | |
Completed |
NCT00318890 -
Cisplatin and Docetaxel Plus Docetaxel and Radiotherapy With Amifostine for Squamous Cell Carcinoma of the Head and Neck
|
Phase 1/Phase 2 | |
Recruiting |
NCT05179824 -
Tempus Priority Study: A Pan-tumor Observational Study
|
||
Recruiting |
NCT05316974 -
Lymphoedema Among Persons With Head- and Neck Cancer
|
||
Not yet recruiting |
NCT03954691 -
Targeting Potassium Channels to Reprogram Glioblastoma Microenvironment: in Vitro and in Vivo Studies
|
||
Active, not recruiting |
NCT03760471 -
Palliative and Oncology Care Intervention: Symptom COACH
|
N/A | |
Completed |
NCT04554667 -
Heavy Lifting Strength Training in Head and Neck Cancer Survivors
|
Phase 1 | |
Completed |
NCT02869399 -
Tertiary Prevention of Head and Neck Cancer With a Dietary Intervention
|
N/A | |
Completed |
NCT02366611 -
Pain Control Using Neuromodulation in Patients Undergoing Definitive Chemoradiotherapy for Head and Neck Cancer
|
N/A | |
Completed |
NCT02075112 -
Soy Isoflavone in Combination With Radiation Therapy and Cisplatin in SCC of the Head and Neck
|
Phase 1 | |
Completed |
NCT00798655 -
Trial of Postoperative Radiation, Cisplatin, and Panitumumab in Locally Advanced Head and Neck Cancer
|
Phase 2 | |
Completed |
NCT02900911 -
Swallowing Rehabilitation in Patients With Head and Neck Cancer Receiving Radiotherapy
|
N/A | |
Completed |
NCT01317589 -
Treatment of Pain in Head-and-Neck Cancer Patients: is Methadone More Effective?
|
Phase 4 | |
Completed |
NCT03841175 -
Forecasts Impact of the Pre-therapeutic TEP-TDM in the 18-FDG Restaging of Upper Aero-digestive Tract Cancers
|