Lornoxicam Versus Etodolac After Third Molar Surgery

Pain, Acute Clinical Trial

Official title:

Comparison of Lornoxicam and Etodolac on Edema, Trismus and Pain After Third Molar Surgery

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05679453
• Other study ID #: 10
• Status: Completed
• Phase: Phase 4
• Start date: July 20, 2022
• Est. completion date: September 29, 2022

Study information

• Verified date: December 2022
• Source: Kutahya Health Sciences University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Our study aimed to compare the effect of lornoxicam and etodolac on postoperative pain, edema and trismus following lower third molar extraction

Description:

20 patients included in study (4 male, 16 female). Lornoxicam and etodolac was given following lower third molar extraction. Pain was evaluated 2., 6., 12., 24., and 48. hours using VAS. Edema was evaluated by measuring tragus-labial commissure, angulus- lateral canthus of eye and angulus mandible-labial commissure. Trismus was evaluated measuring mouth opening by caliper. Edema and Trismus was evaluated by 48. and 168. hours

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: September 29, 2022
• Est. primary completion date: September 25, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 30 Years

Eligibility

Inclusion Criteria:

• Bilateral mesioangular impacted lower third molar

• Asymptomatic Third Molar (No history of infection)

• Systemically Healthy Person

• Person Between aged 18-30

Exclusion Criteria:

• People who are pregnant and lactation process

• People who had any systemic disease

• People who are gastrointestinal problems

• People who are sensitive to drugs used in study

• Lower Third Molar associated with cysts and infections

Related Conditions & MeSH terms

• Acute Pain
• Edema
• Pain, Acute
• Trismus

Intervention

Drug:
• Lornoxicam 8 Mg Oral Tablet
Lornoxicam is a oxicam grup non-steroid antiinflamatuar drug

Locations

Country	Name	City	State
Turkey	Zülfikar Karabiyik	Kutahya

Sponsors (1)

Lead Sponsor	Collaborator
Kutahya Health Sciences University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pain after wisdom tooth extraction	Pain after lower third molar removal, Pain was evaluated with VAS(visual anolog scale)	2 th hours
Primary	Edema after wisdom tooth extraction	Edema lower third molar removal, Edema was evaluated by using reference line on the face	48 th hours
Primary	Trismus after wisdom tooth extraction	Trismus lower third molar removal, trismus was evaluated by using caliper	48 th hours,
Secondary	Pain after wisdom tooth extraction	Pain after lower third molar removal, Pain was evaluated with VAS(visual anolog scale)	6 th hours
Secondary	Pain after wisdom tooth extraction	Pain after lower third molar removal, Pain was evaluated with VAS(visual anolog scale)	12 th hours
Secondary	Pain after wisdom tooth extraction	Pain after lower third molar removal, Pain was evaluated with VAS(visual anolog scale)	24 th hours
Secondary	Pain after wisdom tooth extraction	Pain after lower third molar removal, Pain was evaluated with VAS(visual anolog scale)	48 th hours
Secondary	Edema after wisdom tooth extraction	Edema lower third molar removal, Edema was evaluated by using reference line on the face	168 th hours
Secondary	Trismus after wisdom tooth extraction	Trismus lower third molar removal, trismus was evaluated by using caliper	168 th hours