Pain, Acute Clinical Trial
— KOGISOfficial title:
Kognitivne in Gibalne Prednosti stoječega Delovnega Mesta (KOGIS)
Upright-working has been proven to benefit health by combating the negative effects of physical inactivity. However, long-term commitment to static standing regimens may be limited due to symptoms of musculoskeletal fatigue that may develop during prolonged static standing in the absence of facilitated weight shifting. We propose a dynamic standing approach (working while standing accompanied by small periodic stepping movements) as a more tolerable and thereby more applicative lifestyle modification.
Status | Recruiting |
Enrollment | 20 |
Est. completion date | September 1, 2022 |
Est. primary completion date | September 1, 2022 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 64 Years |
Eligibility | Inclusion Criteria: 1. Healthy adults (both gender, age range 18-64 years) who are currently employed. Exclusion Criteria: 1. Inability to stand or walk without an assistive device 2. History of symptoms in stance that preclude safe and comfortable participation, such as dizziness and lightheadedness, orthostasis, severe symptomatic leg or back musculoskeletal pain, or medication side effects 3. History of symptomatic cardiovascular or pulmonary disease 4. History of rheumatic arthritis 5. History of stroke or other neurologic conditions with residual sensorimotor deficits 6. History of chronic pain syndrome requiring narcotic analgesics 7. Neurological disorders 8. Evidence of dementia 9. Diabetics: low or poorly controlled blood glucose 10. Any other history of medical or psychiatric comorbidity precluding safe participation in the project |
Country | Name | City | State |
---|---|---|---|
Slovenia | Science and research centre Koper | Koper |
Lead Sponsor | Collaborator |
---|---|
Science and Research Centre Koper | University of Michigan |
Slovenia,
Chau JY, van der Ploeg HP, Dunn S, Kurko J, Bauman AE. A tool for measuring workers' sitting time by domain: the Workforce Sitting Questionnaire. Br J Sports Med. 2011 Dec;45(15):1216-22. doi: 10.1136/bjsports-2011-090214. Epub 2011 Sep 22. — View Citation
Cook AJ, Degood DE. The cognitive risk profile for pain: development of a self-report inventory for identifying beliefs and attitudes that interfere with pain management. Clin J Pain. 2006 May;22(4):332-45. — View Citation
Hamilton MT, Hamilton DG, Zderic TW. Role of low energy expenditure and sitting in obesity, metabolic syndrome, type 2 diabetes, and cardiovascular disease. Diabetes. 2007 Nov;56(11):2655-67. Epub 2007 Sep 7. Review. — View Citation
Levine JA, Kotz CM. NEAT--non-exercise activity thermogenesis--egocentric & geocentric environmental factors vs. biological regulation. Acta Physiol Scand. 2005 Aug;184(4):309-18. Review. — View Citation
Levine JA, Schleusner SJ, Jensen MD. Energy expenditure of nonexercise activity. Am J Clin Nutr. 2000 Dec;72(6):1451-4. — View Citation
Waddell G, Newton M, Henderson I, Somerville D, Main CJ. A Fear-Avoidance Beliefs Questionnaire (FABQ) and the role of fear-avoidance beliefs in chronic low back pain and disability. Pain. 1993 Feb;52(2):157-168. doi: 10.1016/0304-3959(93)90127-B. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Overall movement - accelerometry | Overall movement (counts/min) | change in activity levels between all three conditions, which will be measured on average 3 days in-between (maximum length of measurements per subject = 15 days) | |
Primary | Musculoskeletal discomfort | Rate of total musculoskeletal discomfort development (mm/min) | change in musculoskeletal discomfort levels between all three conditions, which will be measured on average 3 days in-between (maximum length of measurements per subject = 15 days) | |
Primary | Leg swelling | Average swelling for both legs (cm) | change in leg swelling levels between all three conditions, which will be measured on average 3 days in-between (maximum length of measurements per subject = 15 days) | |
Secondary | Oxygen uptake | Oxygen uptake VO2 (ml/min/kg) | change in oxygen consumption between all three conditions, which will be measured on average 3 days in-between (maximum length of measurements per subject = 15 days) | |
Secondary | Attention levels | Measuring attention with Stroop test (seconds) | change in attentional levels between all three conditions, which will be measured on average 3 days in-between (maximum length of measurements per subject = 15 days) | |
Secondary | Executive control | Executive functions measured with TMT test (seconds) | change in executive control and cognitive switching levels between all three conditions, which will be measured on average 3 days in-between (maximum length of measurements per subject = 15 days) | |
Secondary | Brain electrocortical activity | EEG measurements (frequency analysis and ERP analysis) | change in electrocortical activity levels between all three conditions, which will be measured on average 3 days in-between (maximum length of measurements per subject = 15 days) |
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