Pain, Acute Clinical Trial
Official title:
Perceptual Distortions in Acute Neck Pain
NCT number | NCT03495076 |
Other study ID # | 1/2018 |
Secondary ID | |
Status | Completed |
Phase | N/A |
First received | |
Last updated | |
Start date | April 20, 2018 |
Est. completion date | July 20, 2018 |
Verified date | August 2018 |
Source | The Jerzy Kukuczka Academy of Physical Education in Katowice |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Research has shown that chronic pain is related to variety of perceptual distortions. Little is known on how acute pain experience influences perception, especially precision of touch. This project is aiming to test the hypothesis of pain as a process of biological value leading to improvement in tactile acuity.
Status | Completed |
Enrollment | 30 |
Est. completion date | July 20, 2018 |
Est. primary completion date | June 15, 2018 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 35 Years |
Eligibility |
Inclusion Criteria: - Only participants without tactile dysfunction will be included. - Participants reporting availability during the days in which the research will be performed. Exclusion Criteria: - current pain experience - episodes of neck - thoracic or lumbar pain lasting more than 24 hours within previous month - history of chronic pain, i.e. pain lasting more than three-month period - comorbidities affecting nervous system - cardio-vascular diseases - psychiatric illnesses - any disease requiring systematic drug consumption - diagnosed scoliosis. |
Country | Name | City | State |
---|---|---|---|
Poland | The Jerzy Kukuczka Academy of Physical Education | Katowice |
Lead Sponsor | Collaborator |
---|---|
The Jerzy Kukuczka Academy of Physical Education in Katowice | University of Luebeck |
Poland,
Adamczyk W, Luedtke K, Saulicz E. Lumbar Tactile Acuity in Patients With Low Back Pain and Healthy Controls: Systematic Review and Meta-Analysis. Clin J Pain. 2018 Jan;34(1):82-94. doi: 10.1097/AJP.0000000000000499. Review. — View Citation
Adamczyk WM, Luedtke K, Saulicz O, Saulicz E. Sensory dissociation in chronic low back pain: Two case reports. Physiother Theory Pract. 2018 Aug;34(8):643-651. doi: 10.1080/09593985.2017.1423431. Epub 2018 Jan 11. — View Citation
Adamczyk WM, Saulicz O, Saulicz E, Luedtke K. Tactile acuity (dys)function in acute nociceptive low back pain: a double-blind experiment. Pain. 2018 Mar;159(3):427-436. doi: 10.1097/j.pain.0000000000001110. — View Citation
Elsig S, Luomajoki H, Sattelmayer M, Taeymans J, Tal-Akabi A, Hilfiker R. Sensorimotor tests, such as movement control and laterality judgment accuracy, in persons with recurrent neck pain and controls. A case-control study. Man Ther. 2014 Dec;19(6):555-61. doi: 10.1016/j.math.2014.05.014. Epub 2014 Jun 10. — View Citation
Harvie DS, Edmond-Hank G, Smith AD. Tactile acuity is reduced in people with chronic neck pain. Musculoskelet Sci Pract. 2018 Feb;33:61-66. doi: 10.1016/j.msksp.2017.11.009. Epub 2017 Nov 21. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Pain intensity measured behaviourally on a Numerical Rating Scale (NRS). | The scale for pain intensity ratings will range from 0 = "no pain" to 10 = "the worst pain imaginable" | Pain intensity will be measured just after saline/sham injection and every 10 seconds after this time point up until 30 seconds. | |
Other | Distribution of pain measured by estimating the diameter of the circle representing area affected by pain. | Greater circle (diameter in cm) will refer to the greater distribution of pain (larger body surface affected). | Pain distribution will be measured just after saline/sham injection and every 10 seconds after this time point up until 30 seconds. | |
Other | Fear of pain measured on a Numerical Rating Scale (NRS) | Fear of pain will be rated on a scale ranging from 0 = "not at all" to 10 = "very much". | Fear of pain (state) measured only at baseline | |
Other | Fear of Pain Questionnaire (FPQ-III). | FPQ-III consists of three subscales measuring: minor pain, severe pain, and medical pain. Each subscale contains 10 items. The total score has a range 30-150. A higher score indicates greater fear of pain. | Measured only at baseline. | |
Other | Pain duration | Pain duration measured by physician in seconds. | One measurement collected immediately after pain alleviation. The time frame will vary from person to person, however it is expected to collect the data an average 10 minutes after the injection. | |
Primary | Tactile acuity measured by two-point discrimination test (TPD). | Mechanical callipers will be delicately applied to the spot just below the location where real or sham injection will be administered. Tactile stimuli will be applied until the very first blanching of the skin. Testing will be commenced with 0 mm between the two calliper's tips, and then the distance between them will be gradually increased until participants will able to verbally report that two points had been touched instead of one. Subsequently, the descending sequence will be applied until the perception of the two points disappeared. | TPD change from baseline at 30 seconds post-manipulation period (e.g. saline injection). | |
Secondary | Laterality judgements measured by left/right recognition application. | A set of images displaying human neck in different orientation in space will be show to participants. The goal of the task is to decide whether given picture depicts neck rotated to the left or right or flexed into left o right side. The accuracy and response time is measured. | Measured at baseline and ~30 seconds after manipulation (e.g. saline injection). | |
Secondary | Sensory dissociation measured by two-point estimation task (TPE). | One tactile stimulus will be applied until the very first blanching of the skin, with a 120 mm horizontal separation between the calipers' tips. Participants will be then asked to indicate with their calipers the distance they have perceived. | Measured at baseline and ~30 seconds after manipulation (e.g. saline injection). |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT05396820 -
Adaptation of the Motor System to Experimental Pain
|
N/A | |
Completed |
NCT04356963 -
Adjunct VR Pain Management in Acute Brain Injury
|
N/A | |
Recruiting |
NCT06350084 -
Effect of Mother's Touch and Nurse's Therapeutic Touch on Pain Level and Crying Time During Heel Blood Collection
|
N/A | |
Completed |
NCT04080037 -
Assessing Opioid Care Practices Using CPV Patient Simulation Modules
|
N/A | |
Recruiting |
NCT05458037 -
RCT of Pain Perception With Fast and Slow Tenaculum Application
|
N/A | |
Completed |
NCT04571515 -
Dose-Response Study of MR-107A-01 in The Treatment of Post-Surgical Dental Pain
|
Phase 2 | |
Completed |
NCT06005480 -
Understanding Rebound Pain After Regional Anesthesia Resolution in Healthy Volunteers
|
Phase 1 | |
Active, not recruiting |
NCT04850079 -
EHR Precision Drug Treatment in Neonates
|
||
Completed |
NCT03272139 -
Interscalene Block Versus Superior Trunk Block
|
Phase 4 | |
Completed |
NCT03271151 -
Effect of Duloxetine on Opioid Use After Total Knee Arthroplasty
|
Phase 4 | |
Recruiting |
NCT05383820 -
Effect of Paracetamol and Ketorolac on RANK-L Levels in Patients Starting Orthodontic Treatment
|
Phase 4 | |
Completed |
NCT04851353 -
Multiple Sensory Interventions On Infants' Pain and Physiological Distress During Neonatal Screening Procedures
|
N/A | |
Completed |
NCT03280017 -
Ketamine With Multilevel Paravertebral Block for Post Video-assisted Thoracic Surgery Pain
|
Phase 4 | |
Completed |
NCT04280796 -
Changes in Affective Pain Processing in Human Volunteers
|
N/A | |
Not yet recruiting |
NCT04523623 -
Pain Control Differences Between Oxycodone and Ibuprofen in Children With Isolated Forearm Injuries
|
N/A | |
Not yet recruiting |
NCT04491630 -
COping With PAin Through Hypnosis, Mindfulness and Spirituality
|
N/A | |
Not yet recruiting |
NCT04062513 -
Olfactive Stimulation Interventions With Mothers' Milk on Preterm Pain Response
|
N/A | |
Withdrawn |
NCT03137030 -
A Comparison of Plasma Concentrations of Hydrocodone and Acetaminophen After Administration of Different Amounts of Tablets of a New and a Marketed Tablet Formulation in Healthy Adults
|
Phase 1 | |
Withdrawn |
NCT03137017 -
A Comparison of Plasma Concentrations of Hydrocodone and Acetaminophen After Administration of a New and a Marketed Tablet Formulation Under Fasted and Fed Conditions in Healthy Adults
|
Phase 1 | |
Completed |
NCT04659395 -
How to Develop a Training Program for Nurses in Ultrasound Guided Femoral Nerve Block
|
N/A |