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Pain, Acute clinical trials

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NCT ID: NCT03187132 Completed - Pain, Acute Clinical Trials

Development and Validation of a Digital Pain-Reduction Kit for Musculoskeletal Injuries

Start date: April 3, 2018
Phase: N/A
Study type: Interventional

This study will test the effectiveness of an evidence-based, multi-modal, "digital pain-reduction kit" as a non-pharmacological supplement to managing patients with pain due to musculoskeletal injuries. Outpatients will be randomized to receive either the pain reduction kit or active control. The kit will contain a virtual reality (VR) headset, therapeutic VR visualization software, and a low-cost wearable transcutaneous electrical nerve stimulation (TENS) unit. Clinical staff will monitor progress and provide scheduled coaching and outreach to patients in the intervention group. The control group will receive the low-cost wearable transcutaneous electrical nerve stimulation (TENS) unit alone; they will not receive VR or remote coaching. Study devices will be delivered to the patient's home with instructions for use; patients will receive remote clinical and technical support. Patients will be followed for 60 days and monitored for functional status, pain levels, use of pain medications (including opioids), satisfaction with care, and time to returning to work.

NCT ID: NCT03178539 Completed - Pain, Acute Clinical Trials

Comparative Study Between the Effect of Diclofanic and Ketorolac in Post Tonsillectomy Pain Management

Start date: January 31, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

Compare between the analgesic efficacy of diclofenac sodium and ketorolac tromethamine in post-tonsillectomy pain management.and Compare between the effect of diclofenac sodium and ketorolac tromethamine on post-tonsillectomy bleeding

NCT ID: NCT03151434 Completed - Pain, Postoperative Clinical Trials

Comparison of Three Different Pain Blocks for Subjects Undergoing VATS (Video Assisted Thoracoscopic Surgery) Procedure.

VATS
Start date: February 7, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare three different pain control methods on subjects who are scheduled to undergo VATS (video-assisted thoracoscopic surgery) procedures. The study will compare their pain scores, narcotic needs, patient satisfaction scores, and narcotic side effects.

NCT ID: NCT03146832 Completed - Pain, Acute Clinical Trials

Therapeutic Strategies During Exposure to Pain in an Experimental Design

Start date: April 1, 2017
Phase: N/A
Study type: Interventional

The goal of the present study is to compare different therapeutic strategies (according to habituation model vs. according to the inhibitory learning approach) during exposure to thermal pain in an experimental design.

NCT ID: NCT03143738 Completed - Postoperative Pain Clinical Trials

Comparison of Regional Anesthesia Techniques After Total Knee Arthroplasty

Start date: April 24, 2017
Phase: N/A
Study type: Interventional

Comparison of continuous adductor canal block to continuous femoral nerve block in patients after total knee arthroplasty. All patients will be anesthetized with spinal anesthesia. Continuous infusion of ropivacaine with a catheter implemented to the adductor canal or next to the femoral nerve. The observed goals: pain intensity, the beginning and quality of rehabilitation.

NCT ID: NCT03131258 Completed - Anxiety Clinical Trials

The Effects of Pre-operative Anxiety on Anesthetic Recovery and Post-operative Pain in Donor Nephrectomy

Start date: June 2014
Phase: N/A
Study type: Interventional

Kidney transplant is the most effective choice of treatment for patients with end-stage kidney failure in terms of quality of life and longevity. Today, 20-25% of kidney transplantations are implemented with living donors. Donor nephrectomy is an operations which has the end goal of a living donor donating one of his kidneys to a patient with end-stage kidney failure (1). Pre-operative anxiety is a condition which is characterized by a random illness, being hospitalised, anesthesia, surgery, or uneasiness or anxiety stemming from not knowing what is to be experienced. Educating and informing in the pre-operative period is the first step in mentally preparing the patient for the operation. In some studies, it has been pointed out that patients who were thoroughly informed in the pre-operative period have lower anxiety levels both in the pre-operative and post-operative periods with also less levels of pain and increased recovery rates in the latter (2). Anesthetic recovery starts at the end of the surgical process and ends with the anesthetized patient completely regaining a wide-awake, responsive state, defensive reflex, and muscle strength. Post-operative pain is acute pain which starts with surgical trauma and ends with tissue healing (3). Providing optimal post-operative analgesia plays an important role in the prevention of post-operative complications (1,4,5). There are studies which examine the link between pre-operative anxiety and post-operative pain (59,74,74,77,78). Patients who will undergo a donor nephrectomy constitute a specific group of patients both because they are not operated due to a health problem that they have and because the operation results with them losing an organ. There are no prospective studies about the effects of pre-operative anxiety on anesthetic recovery and post-operative pain in individuals who have undergone donor nephrectomy in literature. Because of this, we have aimed to research prospectively the effects of pre-operative anxiety on anesthetic recovery and post-operative pain in patients that were to undergo donor nephrectomy surgery.

NCT ID: NCT03127306 Completed - Pain, Acute Clinical Trials

Validation of the Polish Version of BPS (POL-BPS).

POL-BPS
Start date: June 12, 2017
Phase: N/A
Study type: Observational

Between 40 to 70% of patients with critical illness experience moderate to severe pain. Diagnosing pain and assessing its severity is difficult in non-verbal patients both in an Intensive Care Unit and in Postoperative Unit after a major surgery such as cardiac surgery). In patients who are unable to self-report pain, we use behavioural pain scales, namely BPS - Behavioural Pain Scale. Aim: The aim of this study was to validate the Polish version of a behavioural pain assessment method - BPS in intubated, sedated patients after cardiac surgery versus self assessment of pain using Numeric rating scale (NRS) in both delirious and non-delirious patients (assessed using Confusion Assessment Method for ICU, CAM-ICU). Method: A prospective observational cohort study will include 60 patients. The patients will be observed by two trained observers during a nociceptive procedure (position change), both during analgosedation and analgesia. Patients will be observed 5 minutes before, during, and 15 min after the two sets of interventions (six assessments in total). Each BPS assessment will be carried out by two observers blinded to each other. To validate the Polish BPS translation we will use the following methods: calculations of interrater reliability, criterion validity and discriminant validity.

NCT ID: NCT03111342 Completed - Pain, Acute Clinical Trials

Intracervical Anesthesia and Pain Associated With Intrauterine Contraceptive Insertion

Start date: June 1, 2017
Phase: Phase 4
Study type: Interventional

The primary aim of our study is to evaluate the effect of intracervical anesthesia on pain scores immediately following levonorgestrel-releasing intrauterine system (LNG-IUS) insertion in nulligravida women.

NCT ID: NCT03107481 Completed - Pain, Acute Clinical Trials

Acetaminophen IV vs Hydromorphone IV in the ED

Start date: June 4, 2017
Phase: Phase 4
Study type: Interventional

The purpose of the current study is to compare the analgesic efficacy of intravenous acetaminophen and intravenous hydromorphone in the treatment of acute pain in the ED.

NCT ID: NCT03082417 Completed - Pain, Acute Clinical Trials

The PAINFREE Initiative, a Stepped Wedge Cluster Randomized Trial

PAINFREE
Start date: March 1, 2016
Phase: N/A
Study type: Interventional

The PAINFREE (Improving PAIN control following FRactures; towards an Elder-friendly Emergency department) Initiative is a patient-centered multifaceted intervention which aims to improve pain management in patients 75 years and older presenting with a fracture at 7 Emergency Department of participating Montreal hospitals: 1. Montreal General Hospital 2. Royal Victoria Hospital 3. Ste Mary's Hospital 4. Hôpital de Verdun 5. Hôpital du Sacré-Coeur de Montréal 6. Jewish General Hospital 7. Lakeshore General Hospital