Quality of Life Clinical Trial
Official title:
A Cross-over Randomized Controlled Trial of Quality of Life Between Cardiovascular Implantable Electronic Device With and Without Rate Adaptive Pacing
Clinical implantable electronic devices, such as permanent pacemaker, implantable
cardioverter defibrillator and cardiac resynchronization therapy are used in current daily
practice for patients with bradycardia, ventricular arrhythmia, or heart failure. The rapid
progress of permanent pacemaker function is growing to replace human's degenerating
electrophysiology of heart.
The ability of physical work is an important cornerstone of quality of life. In daily
activities, rate response to higher rate is importance for patients with bradycardia who can
not accelerate their heart rate. And rate-adapting pacing of permanent pacemaker is a design
to increase heart rate pacing according to physical activity or emotional activity. Patients
with rate-adaptive pacing will get more cardiac output and overcome the physical activity
such as stair climbing. But there are few studies to evaluate whether the rate-adaptive
pacing of permanent pacemaker will improve the quality of life in people with bradycardia.
The aim of this study is to compare turn-on with turn-off this function (DDDR vs DDD) whether
rate-adaptive pacing will improve quality of life in patients with permanent pacemakers.
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