Oxygen Deficiency Clinical Trial
— OHE-REAOfficial title:
Incidence of Use of High-Flow Nasal Cannula Oxygen Therapy in Intensive Care Units : Prospective, Multi-center, Epidemiological, Uncontrolled Study
Patients with one or more organ failure (heart, lung) require hospitalization in intensive
care where these failures can be managed. Nearly 30% of patients in intensive care units are
hospitalized for acute respiratory distress (lung failure). This failure occurs in about 20%
of postoperative patient, but it can also occur in the context of a pathology specific to the
lung or after weaning of mechanical ventilation.
It is therefore interesting to develop several techniques to provide oxygen to these patients
with the aim in particular to avoid the use of intubation (insertion of a tube into the
trachea to achieve artificial ventilation). For the past ten years, High-Flow Nasal Canula
(HFNC) has developed. This technique reduces the need for intubation but the studies are
contradictory, however they agree on its ease of use and the few risks associated with it.
The principle of this technique is to deliver a humidified and heated gas mixture at a high
rate through large nasal cannula. The advantage of this device is its non-invasive and the
possibility of administering a large amount of oxygen. There is a certain craze for this
oxygenation technique despite few scientific studies in the literature. However, it requires
the expertise of the medical and paramedical team so as not to delay intubation.
The investigators propose to carry out an observational study (without any modification of
the usual practices) with epidemiological aim in order to make an inventory of the modes of
use of the HFNC, in particular on its frequency of use and on its duration of use per patient
hospitalized in intensive care. The investigators will recruit all HFNC patients in intensive
care units (20 centers) (30 patients / center): 15 after weaning of mechanical ventilation
and 15 others for other reasons. Patients will be followed every day and up to 48 hours after
removal of the HFNC.
Status | Recruiting |
Enrollment | 600 |
Est. completion date | December 2, 2020 |
Est. primary completion date | December 2, 2020 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 99 Years |
Eligibility |
Inclusion Criteria: - all adults' patients, admitted to intensive care units treated with HFNC (indication is to discretion of doctor). Exclusion Criteria: - HFNC use for Preoxygenation and Apneic Oxygenation for Intubation - Minor patient, adult patient under guardianship, protected persons, pregnant woman, prior inclusion in the study. |
Country | Name | City | State |
---|---|---|---|
France | CHU de Nantes | Nantes |
Lead Sponsor | Collaborator |
---|---|
Nantes University Hospital |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Incidence of nasal High-Flow Nasal Cannula (HFNC) Oxygen therapy in patients admitted to intensive care | Incidence defined by: the ratio of the number of patients under HFNC on the number of patients admitted to intensive care during the period of inclusion. | 28 days after enrollment |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04597983 -
Effect of 8-week Intake of 2S-hesperidin on Performance, Body Composition and Biochemicals Markers in Amateur Cyclists
|
N/A | |
Recruiting |
NCT05858463 -
High Intensity Interval Training and Muscle Adaptations During PR
|
N/A | |
Completed |
NCT03331471 -
Alveolar Recruitment Maneuver During Pneumoperitoneum
|
N/A | |
Completed |
NCT04626453 -
Oxygenation Changes After 2-month Exercise in Sedentary Older Adults With Diabetes
|
N/A | |
Enrolling by invitation |
NCT04322994 -
THRIVE Use in Pediatric Populations- Multi Site
|
N/A | |
Not yet recruiting |
NCT05578131 -
High-flow Nasal Cannula for Pediatric Anesthetic Induction
|
N/A | |
Completed |
NCT05677009 -
Sustainable Preservation of Essential Oxygen Resources: A Phase 4 Crossover Study of the BUFEO System: SAVE O2
|
N/A | |
Completed |
NCT04612270 -
Quantification of Clinically Relevant Drug Induced Changes in HbO2 Affinity
|
N/A | |
Completed |
NCT04584788 -
Validation of the O3 Regional Somatic Tissue Oxygenation Monitor
|
N/A | |
Completed |
NCT04973046 -
Tissue Oxygen Saturation for Esophagectomy
|
||
Terminated |
NCT03665259 -
Lower Inspiratory Oxygen Fraction for Preoxygenation
|
N/A | |
Recruiting |
NCT03396172 -
FreeDom: Innovative Strategy for the Management of COPD Exacerbations
|
N/A | |
Completed |
NCT03128372 -
Validation of Next Generation Cerebral and Tissue Oximeter
|
N/A | |
Completed |
NCT05430724 -
The Effects of Nicardipine and Esmolol Applied for Controlled Hypotension
|
N/A | |
Recruiting |
NCT05783050 -
Wei Nasal Jet Tube vs Nasal Cannula Oxygen Support in Gastrointestinal Endoscopy Patients
|
N/A | |
Completed |
NCT04711317 -
Pre-oxygenation With High-flow Nasal Cannula in Caesarian Section Under General Anesthesia
|
N/A | |
Completed |
NCT03185507 -
The Effect of Cryotherapy on Cerebral Hemodynamics Within Healthy Subjects
|
Phase 1 | |
Completed |
NCT04266665 -
Effect of Dexmedetomidine on Brain Homeostasis and Neurocognitive Outcome
|
Phase 4 | |
Completed |
NCT06371651 -
Creatine and GAA for Brain Oxygenation
|
N/A | |
Completed |
NCT05866289 -
Awake Prone Positioning for COVID-19 Acute Hypoxaemic Respiratory Failure
|