Oxidative Stress Clinical Trial
Official title:
Randomized Clinical Trial of the Effect of G. Mangostana L Rind and Solanum Lycopersicum Fructus Extract to Prevent Exercise-induced Oxidative Stress
Treatments are an administration of a mixed extract of Garcinia mangostana 400mg and Solanum Lycopersicum Fructus 200mg (OKSI(R) POM TR 193324351) and placebo control.
Double-blinded Randomized Clinical Trial
The population of study will involve sedentary men, the student in Universitas Negeri
Semarang aged 18-25 years old, targetted populations are 30 subjects consist of 15 treatment
group and the rest 15 placebo-control group. Voluntary sampling will be conducted.
Information to the candidates delivered directly, leaflets, and social media broadcasting.
Two arm treatment to be given is an administration of a mixture extract of Garcinia
mangostana 400mg and Solanum Lycopersicum Fructus 200mg (OKSI(R) POM TR 193324351) and
placebo control.
The administration of extract treatment and placebo will be given for four weeks.
The primary effect that will be observed is the changes in malondialdehyde (MDA) and
high-sensitivity Cardiac-Troponin I (hs-cTnI) level after an ergo-cycle exercise test.
The secondary effect of the treatment that will be observed is the baseline and
post-treatment parameters of MDA levels.
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