AS900672-Enriched in Ovulation Induction

Status Terminated

Clinical Trial Summary

This is a Phase 2, interventional, multi-center, randomized, assessor-blind, active-comparator, dose-finding study to evaluate a new investigational long-acting follicle stimulating hormone (FSH) in oligo-anovulatory women undergoing ovulation induction (OI). This study will compare 4 doses of the investigational drug versus a currently marketed drug follitropin alfa (Gonal-f ®) prefilled pen with regards to ovulation rate.

Clinical Trial Description

The study was terminated after Merck Serono had taken the decision not to pursue the development of AS900672-enriched in ovulation induction (OI). This decision was not related to any safety or efficacy concerns over the use of AS900672-Enriched in OI. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Ovulation Induction

Clinical Trial Details

NCT number	NCT00553514
Study type	Interventional
Source	Merck KGaA
Contact
Status	Terminated
Phase	Phase 2
Start date	December 2007
Completion date	March 2009

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT01008319` - Traditional Clomiphene Citrate Administration vs. Stair-step Approach	Phase 3
Terminated	`NCT01075815` - A Clinical Trial to Determine the Effect of Lutropin Alfa on Embryo Quality and Implantation Rate in Advanced Reproductive Age	Phase 2
Terminated	`NCT01079949` - A Phase II Study to Assess the Efficacy and Safety of Luveris® (Lutropin Alfa) in Mid Follicular Phase for Controlled Ovarian Stimulation (COS) in Advanced Reproductive Age	Phase 2
Completed	`NCT01081639` - To Evaluate the Convenience, Safety and Efficacy of Follitropin Alfa Liquid Pen Compared With Follitropin Beta Liquid Pen	Phase 3
Terminated	`NCT00697255` - A Phase 2 Trial to Evaluate if Corifollitropin Alfa (Org 36286), Followed by a Low Daily Dose of hCG or Recombinant FSH Can Induce Monofollicular Growth in Women With WHO Group II Anovulatory Infertility (P05693)	Phase 2
Completed	`NCT01183143` - Convenience and Safety of Assisted Reproductive Technology Procedures Using a Gonal-F Filled by Mass (Fbm) Liquid Formulation Applied by Pen for Ovulation Induction and In-vitro Fertilization	Phase 3
Completed	`NCT01081626` - Recombinant Follicle Stimulating Hormone (FSH) (Gonal-f®): Use in Ovulation Induction	Phase 4
Completed	`NCT01111084` - A Prospective, Multi-centric Observational Study to Determine the Mono-bifollicular Development in Infertile Women Subjected to Ovulation Induction With Follitropin α	N/A
Completed	`NCT04834791` - Letrozole Versus Gonadotropins in Clomiphene Citrate Resistance	Phase 4
Recruiting	`NCT02496754` - The Application of a New Ovarian Stimulation Protocol in IVF	N/A
Completed	`NCT01645241` - Evolutive Potential of Embryos Obtained From Oocytes After Luteal Phase Ovarian Stimulation	N/A
Terminated	`NCT04306692` - Myo-inositol Versus Clomiphene Citrate in PCOS	Phase 4
Recruiting	`NCT03396380` - Effect of Vitamin D Supplement in Induction of Ovulation in Overweight Women With Polycystic Ovary Syndrome	Phase 3
Terminated	`NCT00823472` - Trial Comparing Start Stimulation of Recombinant Follicle Stimulating Hormone (rFSH) on Cycle Day 2 Versus Cycle Day 5 in In Vitro Fertilization (IVF)	Phase 4
Completed	`NCT01110707` - A Randomised, Phase II, Comparative Study With a Parallel Control for Evaluating the Efficacy and Safety of Combined Treatment of Lutropin Alpha and Recombinant Human Luteinizing Hormone in the Middle of the Controlled Ovarian Stimulation Follicular Phase in Women With Reduced Ovarian Reserve	Phase 2
Completed	`NCT04610957` - Effect of Adding Isoflavonoids to Clomiphene Citrate for Ovulation Induction in Women With Polycystic Ovary Syndrome	N/A
Completed	`NCT01185782` - SJ-0021 (Gonalef®) Versus Purified Pituitary Gonadotropin (Fertinorm-P®) for Ovulation Induction in Japanese Infertile Women	Phase 3
Completed	`NCT01152866` - An Open Label, Canadian Phase IIIb Study With Ovidrel in Ovulation Induction (OI) and Assisted Reproductive Technique (ART)	N/A
Not yet recruiting	`NCT03307720` - Agonist Versus Classical HCG Trigger (Poor Responders, Normoresponders and High Responders)	N/A
Completed	`NCT03825445` - GnRH Agonist Versus hCG Trigger in Ovulation Induction With Intrauterine Insemination.	N/A