Ovarian Stimulation Clinical Trial
— TAILOfficial title:
Conventional Ovarian Stimulation vs. Single Injection Stimulation of Corifollitropin Alfa in Oocyte Donor. A Randomized Clinical Trial. TAIL Study
Verified date | May 2021 |
Source | Instituto Bernabeu |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study aims to study the efficiency of using a single injection of Corifollitropin alfa for ovarian stimulation by initiating administration late and without further administration of follicle-stimulating hormone after the 7th day of stimulation compared to conventional ovarian stimulation using Corifollitropin alfa (drug administration 5 days after cessation of hormonal contraceptive and supplementation with follicle-stimulating hormone daily administration from the 8th day of stimulation). This a controlled randomized clinical study and 180 patients will be recruited (90 per arm) and the primary study outcome is the number of obtained oocytes.
Status | Completed |
Enrollment | 180 |
Est. completion date | May 8, 2021 |
Est. primary completion date | May 8, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 18 Years to 32 Years |
Eligibility | Inclusion Criteria: - Eligible for oocyte donation program - Age between 18 and 32 years old - BMI >18 and <30 - Antral follicle count >12 (summing both ovaries) - Presence of both ovaries - Ability to participate in and comply with study protocol - Signed informed consent - No treatment with ovulation stimulators in the 3 months prior to the start of stimulation. Exclusion Criteria: - Diagnosis of endometriosis at any stage - AFC >20 - Polycystic ovary syndrome - Concurrent participation in another study |
Country | Name | City | State |
---|---|---|---|
Spain | Instituto Bernabeu | Alicante |
Lead Sponsor | Collaborator |
---|---|
Instituto Bernabeu |
Spain,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Number of oocytes | Number of oocytes after stimulation | At the end of stimulation |
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