Dehydroepiandrosterone Supplementation for Poor Responder Patients During in Vitro Fertilization Treatment

Ovarian Stimulation Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01145144
• Other study ID #: mmc07204-2006ctil
• Status: Completed
• Phase: N/A
• First received: May 3, 2010
• Last updated: June 15, 2010
• Start date: January 2008
• Est. completion date: July 2009

Study information

• Verified date: June 2010
• Source: Meir Medical Center
• Contact: n/a
• Is FDA regulated: No
• Health authority: Israel: Ethics Commission
• Study type: Interventional

Clinical Trial Summary

The aim of this study was to evaluate the effect of dehydroepiandrosterone supplementation on in vitro fertilization performance and outcome among poor-responder patient.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 0
• Est. completion date: July 2009
• Est. primary completion date: July 2009
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years to 42 Years

Eligibility

Inclusion Criteria:

• previous poor response to ovarian stimulation in IVF.

Exclusion Criteria:

• patients over the age of 42

• patients who received DHEA at any time.

Study Design

Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Ovarian Stimulation

Intervention

Drug:
• dehydroepiandrosterone crystalline fine powder

Locations

Country	Name	City	State
Israel	Meir Medical center IVF unit	kfar Saba
Israel	Meir Medical Center	Kfar Sava

Sponsors (1)

Lead Sponsor	Collaborator
Meir Medical Center

Country where clinical trial is conducted

Israel, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	peak estradiol level.			No
Primary	number of retrieved oocytes.			Yes
Primary	Embryos that were graded as a top quality (according to the number of cells and percent of fragmentation)			Yes
Primary	number of embryos reserved for transfer.			Yes
Secondary	pregnancy rate.			Yes
Secondary	live birth rate.			Yes