Evaluation of the Ovarian Reserve in Patients Who Hypogastric Arteries and or Uterine Arteries Had Been Ligated

Ovarian Reserve Clinical Trial

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02995343
• Other study ID #: 2.100.2014.0076
• Status: Recruiting
• Phase: N/A
• Start date: November 2016
• Est. completion date: September 2019

Study information

• Verified date: March 2019
• Source: Ege University
• Contact: cagdas sahin, MD
• Phone: +905324676106
• Email: cagdasdr[@]yahoo.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Patients who hypogastric arteries and/or uterine arteries had been ligated will be evaluated in terms of ovarian reserve markers such as anti-mullerian hormone levels, ovarian volumes, antral follicule count, follicule stimuli hormone and estrogen levels. Investigators will search their archives for finding suitable patients for study. Investigators will especially notice being at least 6 month time of interval between surgery and evaluation time. Ultrasound examination and taking blood sample will be performed on 2nd or 3th day of menstrual cycle. These results will be compared with normal postpartum women's results. It will be evaluated that there is or not any effect of the hypogastric arteries and/or uterine arteries on ovarian reserve

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 40
• Est. completion date: September 2019
• Est. primary completion date: August 2019
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• Patients had been ligated hypogastric and/or uterine arteries

• Patients are in 6 month period after surgery

• Without performed hysterectomy

• No older than 40 years old

• No history about endocrinopathy which have an effect upon ovarian reserve

Exclusion Criteria:

• Patients had been made other gynecologic surgery such as fallopian tube ligation and hysterectomy etc.

• Patients are older than 40 years old

• Patients use drugs which have an effect upon ovarian reserve

• Patients have diseases which have an effect upon ovarian reserve such as some endocrinopathy, malign diseases which require radiotherapy and chemotherapy etc.

Related Conditions & MeSH terms

• Hypogastric Artery Ligation
• Ovarian Reserve
• Uterine Artery Ligation

Intervention

Procedure:
• Hypogastric and/or uterine artery ligation

Locations

Country	Name	City	State
Turkey	Ege University, Medicine Faculty, Department of Obstetrics and Gynecology	Izmir

Sponsors (1)

Lead Sponsor	Collaborator
Ege University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Anti-mullerian hormone levels will be evaluated		6 months after surgery and delivery
Primary	Antral Follicule Count will be evaluated		6 months after surgery and delivery
Primary	Ovarian volume will be evaluated		6 months after surgery and delivery
Primary	Follicule Stimuli Hormone levels will be evaluated		6 months after surgery and delivery
Primary	Estrogen levels will be evaluated		6 months after surgery and delivery