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Ovarian Germ Cell Tumor clinical trials

View clinical trials related to Ovarian Germ Cell Tumor.

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NCT ID: NCT06276491 Recruiting - Ovarian Cancer Clinical Trials

Phase 1, Safety and Tolerability Study of XmAb®541 in Advanced Solid Tumors

Start date: April 4, 2024
Phase: Phase 1
Study type: Interventional

The primary purpose of this study is to determine whether the investigational drug XmAb541 is safe and well tolerated, and to determine an optimal and safe dose(s) for further study. The study will also evaluate effect of XmAb541 on tumor outcomes.

NCT ID: NCT05500391 Recruiting - Glioma Clinical Trials

Assessment of Compliance With Monitoring Conducted by a Physician in Person or by a Nurse in Remote Monitoring

SUR-CAN
Start date: February 28, 2024
Phase: Phase 2
Study type: Interventional

This is a multicenter, interventional, randomized study among adult patients recently diagnosed with a rare tumor (<12 months). The study will aim to compare compliance with the personalized post-treatment surveillance plan, established for each patient according to national guidelines, when the surveillance is conducted in person by a hospital-based physician (control arm) or remotely by a trained nurse (experimental arm).

NCT ID: NCT04876456 Recruiting - Germ Cell Tumor Clinical Trials

A Phase II Trial of Cabozantinib With Patients With Refractory GCTs

Start date: June 10, 2021
Phase: Phase 2
Study type: Interventional

The purpose of the CTO-IUSCCC-0752 study is to investigate the use of Cabozantinib for patients with incurable, refractory germ cell tumors. Patients will be treated until evidence of disease progression, non-compliance with study protocol, unacceptable major toxicity, at subject's own request for withdrawal, or if the study closes for any reason.

NCT ID: NCT04804007 Recruiting - Germ Cell Tumor Clinical Trials

Maintenance Oral Etoposide or Observation Following High-dose Chemo for GCT

Start date: March 3, 2021
Phase: Phase 2
Study type: Interventional

This is an open label randomized phase II trial of maintenance oral etoposide vs. observation in patinets with relapsed GCT treated with high-dose chemotherapy (HDCT) and peripheral-blood stem-cell transplant (PBSCT).