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Maintenance Oral Etoposide or Observation Following High-dose Chemo for GCT

Germ Cell Tumor Clinical Trial

Official title:
Randomized Phase 2 Trial of Maintenance Oral Etoposide or Observation Following High-dose Chemotherapy for Relapsed Metastatic Germ-Cell Tumor

Clinical Trial Summary

This is an open label randomized phase II trial of maintenance oral etoposide vs. observation in patinets with relapsed GCT treated with high-dose chemotherapy (HDCT) and peripheral-blood stem-cell transplant (PBSCT).

Clinical Trial Description

This is a randomized phase 2 trial of maintenance etoposide versus observation following HDCT+PBSCT for relapsed GCT. Patients who completed HDCT+PBSCT within the past 16 weeks will enroll and randomize in 1:1 fashion to maintenance daily oral etoposide 50mg vs. observation only. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04804007
Study type Interventional
Source Indiana University
Contact Christin Snow, RN
Phone 317-274-5830
Email chsnow@iu.edu
Status Recruiting
Phase Phase 2
Start date March 3, 2021
Completion date December 2028
View Details
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