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Ovarian Cysts clinical trials

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NCT ID: NCT03370952 Completed - Ovarian Cysts Clinical Trials

Laparoscopy-assisted Ovarian Cystectomy: NEW APPROCH

Start date: December 21, 2017
Phase: N/A
Study type: Interventional

Under general anaesthesia, the patient is placed in the modified dorsal lithotomy position a 10-mm umbilical trocar is inserted. A panoramic view of the pelvis was obtained together with full assessment of the ovarian mass(es). Aspiration of the cyst: Veress needle is inserted in the midline 2 cm above the symphysis pubis to aspirate the cyst under laparoscopic guidance (to guide the entry of the needle into the cyst wall & to confirm complete aspiration). Delivery of affected ovary outside the abdominal cavity: Classic ovarian cystectomy will be done using microsurgical techniques in which the cyst wall will be dissected gently and carefully from the healthy ovarian tissue followed by perfect haemostasis and re-fashioning of the remaining ovarian tissue using Vicryl (3-0) sutures. Re-introduction of the ovary to inside the abdominal cavity: The stitched ovary is pushed gently inside the abdominal cavity and the mini-laparotomy is re-covered by the rubber shield (to allow re-inflation of the abdominal cavity). The ovary is reassessed under laparoscopic guidance to ensure perfect haemostasis and normal position of the ovary. Pelvic irrigation is done if needed.

NCT ID: NCT03189316 Terminated - Clinical trials for Chronic Renal Insufficiency

Anti-inflammatory Cells in Peritoneal Cavity

Start date: June 6, 2017
Phase: N/A
Study type: Interventional

Some subsets of lymphocytes are able to inhibit immune response and thus, could be used to control auto-immune diseases and transplant reject. In mice, the main source of those anti-inflammatory lymphocytes is the peritoneal cavity. No data are available in human. This study aims at exploring the presence of those anti-inflammatory lymphocytes in human peritoneal cavity and at determine how to expand those cells.

NCT ID: NCT02890914 Completed - Ovarian Cysts Clinical Trials

Transvaginal Ultrasound Training for Obstetrics and Gynecology Residents

Start date: September 2012
Phase: N/A
Study type: Interventional

Obstetrics and gynecology residents are deemed to be proficient in transvaginal ultrasound (TVUS) upon graduation from an accredited program, although TVUS education in residency is not standardized. The objective of this study is to assess for improvement in transvaginal ultrasound knowledge among residents after viewing an educational DVD.

NCT ID: NCT02852447 Completed - Ovarian Cysts Clinical Trials

The Effect of Surgery for Non Endometriosic Ovarian Cysts on Ovarian Reserve

Start date: November 2014
Phase: N/A
Study type: Observational

The main objective is to evaluate the ovarian reserve after laparoscopic cystectomy. The secondary objective is the analysis of predictors of change in the ovarian reserve after surgery

NCT ID: NCT02835391 Completed - Cancer Clinical Trials

PerClot Compared to Usual Care in Gynaecology Procedures

Start date: November 2015
Phase: N/A
Study type: Interventional

This study is a post market, multi-centre, randomised study evaluating PerClot compared to usual care. PerClot is a CE marked device and is currently used as a haemostat in gynaecological surgery throughout Europe. The purpose of this study is to collect additional post market data on its use in this indication.

NCT ID: NCT02831556 Completed - Pregnancy Clinical Trials

Point of Care 3D Ultrasound for Various Applications: A Pilot Study

Start date: July 2016
Phase:
Study type: Observational

Summary 1. Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound in obtaining abdominal and/or pelvic images. The study will use a newly developed acquisition method and post-processing technique to create three dimensional image models of the abdomen and/or pelvis. 2. Study activities and population group. The study population will be a convenience sample of patients of any age presenting to the Emergency Department with complaints necessitating a clinical abdominal and/or pelvic imaging. The study intervention includes acquisition of research ultrasound images, which will not be used for clinical care, and comparison of these images with clinically obtained images. Other clinical data such as surgical and pathology reports will also be reviewed. 3.Data analysis and risk/safety issues. This is a pilot study intended to determine feasibility and to refine image reconstruction algorithms. Research images will be compared to clinical images. Comparison of research images with final diagnosis will also occur. The research intervention, an ultrasound exam, has no known safety risks. The only risk to subjects is loss of confidentiality. This study is observational, not interventional, because the experimental ultrasound will be performed in all subjects and will not be used in the clinical care of patients (consequently, will not have the opportunity to affect clinical outcomes). Experimental images will be reviewed after completion of clinical care and will not be provided to the clinicians caring for the subjects. The investigators are not measuring the effect of the ultrasound examination on the subjects' outcomes.

NCT ID: NCT02482467 Recruiting - Ovarian Cyst Clinical Trials

Prognosis and Long Term Pubertal Outcome of Girls Previously Diagnosed With a Prenatal Ovarian Cyst

KYSTOV
Start date: November 24, 2014
Phase: N/A
Study type: Interventional

Puberty and long-term ovarian function of patients with a ovarian prenatal cyst has not described to date.

NCT ID: NCT02218502 Terminated - Ovarian Cancer Clinical Trials

Study Into a New Diagnostic Tool (Simple Ultrasound-based Rules) in Patients With Adnexal Masses

SUBSONiC
Start date: September 2014
Phase: N/A
Study type: Interventional

This study is performed to compare the diagnostic performance and cost-effectiveness of different diagnostic methods for differentiating benign from malignant adnexal (ovary or Fallopian tube) masses: the Risk of Malignancy Index (RMI) will be compared with a two-step triage test called "simple ultrasound-based rules" supplemented -if necessary- with either subjective assessment by an expert sonographer or Diffusion Weighted - Magnetic Resonance Imaging (DW-MRI). The investigators will test the hypothesis that this two-step triage test will have better diagnostic accuracy than the RMI and therefore will improve the management of women with adnexal masses.

NCT ID: NCT02155777 Completed - Ovarian Cancer Risk Clinical Trials

Why do Oral Contraceptives Prevent Ovarian Cancer?

Start date: June 2014
Phase: Early Phase 1
Study type: Interventional

Use of oral contraceptives (OCs) reduces a woman's risk of ovarian cancer very significantly and the protective effect continues for at least 25 years after use of OCs is stopped; the mechanisms of how this occurs are not understood. We are proposing here to directly study the effect of OCs on the fallopian tube and inclusion cysts within the ovary - sites from which most ovarian cancers are thought to arise - in order to better understand the mechanistic basis for OC protection against ovarian cancer. We think the protection results from reduced cell proliferation. It will lay the foundation for further studies to ensure that the protection against ovarian cancer afforded by 'traditional' OCs is not lost with alterations in OC formulation, and, if possible, to guide development of OC formations to improve further on the protection afforded by OCs.

NCT ID: NCT02129036 Completed - Ovarian Cysts Clinical Trials

Ovarian Clear Cell Adenocarcinoma Review

OCCA
Start date: April 2008
Phase:
Study type: Observational

Clear cell carcinoma comprises 5-10% of surface epithelial ovarian cancers, and about 30-40% of the patients with clear cell carcinoma are diagnosed in the advanced stage. The investigators studied the response to chemotherapy and survival for either paclitaxel-platinum based chemotherapy or conventional platinum-based chemotherapy among all stages clear cell ovarian carcinoma. Prognostic factors for survival among the patients with pure, advanced, clear cell ovarian carcinoma were also evaluated.