Ovarian Carcinoma Clinical Trial
Official title:
Circulating Tumor DNA as an Early Marker of Recurrence and Treatment Efficacy in Ovarian Carcinoma
Prospective multicentre assay to assess ctDNA value for ovarian cancer monitoring and disease recurrence after front-line treatment.
The main objective is to explore the capacity of ctDNA to be an early marker of ovarian
carcinoma recurrence after front-line treatments, i.e. to show significant modifications
before clinical diagnosis of disease relapse.
Prospective multicentre open-label study
During visits in the frame of management of the disease, blood samples will be collected at
diagnosis, after each cycle of eventual neoadjuvant chemotherapy, every 6 months during the
following 2 years, and every year during the remainin time of follow-up. Tumor samples will
be collected at surgery or through a biopsy.
Patients will then have a standard care follow-up for a period of 5 years.
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