APP-based Emotion Recognition Training Improve ASD Social Function

Autism Spectrum Disorder High-Functioning Clinical Trial

Official title:

APP-based Emotion Recognition Training Improve ASD Social Function

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06421272
• Other study ID #: UESTC-neuSCAN-94
• Status: Recruiting
• Phase: Phase 1
• Start date: January 1, 2023
• Est. completion date: May 31, 2024

Study information

• Verified date: May 2024
• Source: University of Electronic Science and Technology of China
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The main aim of the study is to investigate whether APP-based emotional recognition training improve social function in autistic children.

Description:

50 ASD children age ranged from 4-10 years old will be randomly allocated to either app-based emotional recognition training or memory training groups for 2 months. Before and after training, some assessements were measured including Autism Diagnostic Observation Schedule-2, Childhood Autism Rating Scale, Wechsler Intelligence Scale and Psychoeducational Profile-3. Some other questionnaires are also collected including Social Responsibility Scale-2,Repetitive behavior scale-Revised,Caregiver Strains Questionnaire，Social Communication Questionnaire，Social Anxiety Scale for Children，Adaptive behavior assessment Schedule. Four eye-tracking tasks as follows: (1) Dynamic geometrical paired with dynamic child dancing; (2) Static neutral and emotional faces; (3) A dynamic gaze-following task; (4) social interaction behaviors paired with the toys alone; (5) spinning actions conducted via children paired with objects.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 50
• Est. completion date: May 31, 2024
• Est. primary completion date: May 31, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 4 Years to 10 Years

Eligibility

Inclusion criteria: Clinical diagnosis of Autism Spectrum Disorder and follow these criteria: (1) Age range: 4-10 years old, gender not limited;(2) Ethnicity: Han nationality;(3) Autism Diagnostic Observation Schedule-Second Edition (ADOS-2) Comparison Score greater than or equal to 5 points (Le et al., 2022);(4) Considering that only high-functioning autism individuals can successfully complete the eye-tracking tasks, children with a Wechsler score greater than or equal to 60 points are selected; Exclusion criteria: (1) No neurological complications, such as epilepsy, cerebral palsy, fragile X syndrome, etc.;(2) No prior medical interventions, such as taking antipsychotic drugs, receiving transcranial magnetic stimulation, acupuncture, etc.;(3) No abnormal imaging diagnosis or any brain injury.

Related Conditions & MeSH terms

• Autism Spectrum Disorder
• Autism Spectrum Disorder High-Functioning

Intervention

Behavioral:
• APP-based emotion recognition intervention
ASD children were asked to play emotion recognition-related games for eight weeks using iPAD. Two 15-minsute sessions each day was required.
• APP-based memory intervention
ASD children were asked to play memory-related games for eight weeks using iPAD. Two 15-minsute sessions each day was required.

Locations

Country	Name	City	State
China	University of Electronic Science and Technology	Chendu	Sichuan

Sponsors (1)

Lead Sponsor	Collaborator
University of Electronic Science and Technology of China

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Other questionnaires and assessment	CARS	1-2 hour
Other	Other questionnaires and assessment	PEP-3	1-2 hour
Other	Other questionnaires and assessment	RBS-R	1-2 hour
Other	Other questionnaires and assessment	SCQ	1-2 hour
Other	Other questionnaires and assessment	CSQ	1-2 hour
Primary	ADOS-2 assessment	ADOS-2 assessment	1-2 hour
Primary	SRS-2	SRS-2	half an hour
Secondary	Visual performance across five tasks based on eye-tracking	Tasked based eye-tracking performance including fixation time, fixation counts	half an hour