Metastatic Castration-resistant Prostate Cancer (mCRPC) Clinical Trial
Official title:
A Phase 1, Multi-center, Open-label, Dose-escalating Study to Evaluate the Safety and Tolerability of Triple Combination Regimen of SL-T10, GX-I7 and Pembrolizumab in Patients With Metastatic Castration-resistant Prostate Cancer (mCRPC)
The purpose of this study is to evaluate the efficacy and safety of SL-T10 and GX-I7 or SL-T10, GX-I7 and pembrolizumab in patients with metastatic castration-resistant prostate cancer (mCRPC).
The purpose of this study is to evaluate the safety, tolerability, and preliminary efficacy of SL-T10, GX-I7, and pembrolizumab in combination in patients with metastatic castration-resistant prostate cancer (mCRPC). ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05107674 -
A Study of NX-1607 in Adults With Advanced Malignancies
|
Phase 1 | |
| Completed |
NCT01977651 -
A Study to Evaluate the Potential Increased Risk of Seizures Among Metastatic Castration-Resistant Prostate Cancer (mCRPC) Patients Treated With Enzalutamide
|
Phase 4 | |
| Recruiting |
NCT04015622 -
PROstate Cancer TReatment Optimization Via Analysis of Circulating Tumour DNA
|
Phase 2 | |
| Recruiting |
NCT05983198 -
A Phase I/II, Open-label, Multi-center Study of [225Ac]Ac-PSMA-R2 in Men With PSMA-positive Prostate Cancer With or Without Prior 177Lu-PSMA Radioligand Therapy.
|
Phase 1/Phase 2 | |
| Not yet recruiting |
NCT06134232 -
Metastatic Castrate-Resistant Prostate Cancer Subjects Treated With PROVENGE® + One Infusion of Sipuleucel-T
|
Phase 3 | |
| Recruiting |
NCT06126731 -
Combination Study of Antibiotics With Enzalutamide (PROMIZE)
|
Phase 1/Phase 2 | |
| Recruiting |
NCT05806814 -
Sipuleucel-T Based Autologous Cellular Immunotherapy for Advanced Prostate Cancer
|
Phase 1 | |
| Recruiting |
NCT05658003 -
A Study Evaluating [177Lu]Lu-PSMA-617 vs. a Change of Androgen Receptor-directed Therapy in Taxane Treatment Naive Chinese Male Patients With Progressive Metastatic Castrate Resistant Prostate Cancer
|
Phase 2 | |
| Active, not recruiting |
NCT05670106 -
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Dosimetry of [177Lu]Lu-PSMA-617 in Chinese Adult Male Patients With Progressive PSMA-Positive mCRPC
|
Phase 2 | |
| Recruiting |
NCT06334432 -
Safety and Efficacy Study of NUV-1511 in Adult Patients With Advanced Solid Tumors
|
Phase 1/Phase 2 | |
| Recruiting |
NCT04691804 -
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study of Fuzuloparib Combined With Abiraterone Acetate and Prednisone (AA-P) Versus Placebo Combined With AA-P as First-Line Treatment in Patients With Metastatic Castration-Resistant Prostate Cancer
|
Phase 3 | |
| Completed |
NCT03896984 -
Descriptive Analysis of Clinical Outcomes in Patients With Prostate Gland Cancer, Which Spreads to Other Parts of the Body, Who Were Treated First With Novel Anti-hormone Therapy Followed by a Second Line Treatment With Novel Anti-Hormone Therapy or RadIum-223 (Xofigo).
|
||
| Completed |
NCT03074032 -
Safety, Tolerability and Pharmacokinetics of ONC1-0013B in Patients With Progressive Metastatic Castration-resistant Prostate Cancer
|
Phase 1 | |
| Recruiting |
NCT05032040 -
A Study of XmAb20717 (Vudalimab)in Patients With Selected Advanced Gynecologic and Genitourinary Malignancies
|
Phase 2 | |
| Completed |
NCT03071328 -
INJECT: A Pilot Study of Intra-tumoral Injections in Metastatic Urological Cancers
|
Early Phase 1 | |
| Active, not recruiting |
NCT02649790 -
Study of the Safety, Tolerability and Efficacy of KPT-8602 in Participants With Relapsed/Refractory Cancer Indications
|
Phase 1/Phase 2 | |
| Completed |
NCT03030885 -
Use of an Experimental Radiopharmaceutical (131I-MIP-1095) in Men With Metastatic Castration-Resistant Prostate Cancer (mCRPC)
|
Phase 1 | |
| Terminated |
NCT03712930 -
Treatment of Metastatic Castration-Resistant Prostate Cancer With Homologous Recombination Deficiency
|
Phase 2 | |
| Recruiting |
NCT06241846 -
A Phase II Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of YL201 in Patients With mCRPC
|
Phase 2 | |
| Recruiting |
NCT03903835 -
ProBio: A Biomarker Driven Study in Patients With Metastatic Prostate Cancer
|
Phase 3 |