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Clinical Trial Summary

CB-012 is an allogeneic chimeric antigen receptor (CAR-T) cell therapy that targets C-type lectin-like molecule-1 (CLL-1). This is a Phase 1 study to evaluate the safety, preliminary efficacy, and pharmacokinetics, of CB-012 (the study treatment) in adults with acute myeloid leukemia (AML) that has come back after prior treatment (relapsed) or did not respond or is no longer responding to other treatment (refractory). Participants must have received at least 1 but not more than 3 prior lines of treatment for AML .


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06128044
Study type Interventional
Source Caribou Biosciences, Inc.
Contact Caribou Biosciences
Phone 510-982-6030
Email clinicaltrials@cariboubio.com
Status Recruiting
Phase Phase 1
Start date February 8, 2024
Completion date April 2028

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