Subarachnoid Hemorrhage, Aneurysmal Clinical Trial
Official title:
Pterygopalatine Fossa Block in Aneurysmal Subarachnoid Hemorrhage
Aneurysmal subarachnoid hemorrhage (aSAH) can cause a severe headache (HA) that is famously treatment-resistant. Current pain regimens are too reliant on opioids, which results in long-term opioid dependence and can obfuscate the neurological examination, which is critical to detect vasospasm and delayed cerebral ischemia. This study will gather the initial evidence of whether the pterygopalatine fossa (PPF) regional anesthesia nerve block can treat aSAH-related HA and reduce opioid consumption in patients with aSAH.
Status | Recruiting |
Enrollment | 10 |
Est. completion date | July 1, 2024 |
Est. primary completion date | July 1, 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Aneurysmal subarachnoid hemorrhage with secured aneurysm - Age greater than or equal to 18 years - Able to communicate pain level Exclusion Criteria: - Documented allergy to local anesthetics (e.g. bupivicaine) - Patients with unsecured aneurysms - Patients who are unable to communicate pain level (e.g. sedation/mechanical ventilation/delirium, etc) - Medical treatment for vasospasm including blood pressure/inotropic augmentation - Angiographic treatment for vasospasm within 48 hours |
Country | Name | City | State |
---|---|---|---|
United States | UT Southwestern | Dallas | Texas |
Lead Sponsor | Collaborator |
---|---|
University of Texas Southwestern Medical Center |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Opioid consumption | 3 days | ||
Primary | Pain Rating Scale | Scale of 1-10, 1 being lowest possible pain, 10 being highest possible pain | 3 days |
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