Functional Outcome After Minimally Invasive Pyeloplasty for Adult Patients With UPJO

Ureteropelvic Junction Obstruction Clinical Trial

Official title:

Functional Outcome After Laparoscopic and Robot Assisted Management of Uretero-pelvic Junction Obstruction Disease Caused by Crossing Vessels for Adult Patients

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05895422
• Other study ID #: MD-85-2023
• Status: Recruiting
• Phase: Phase 3
• Start date: June 1, 2023
• Est. completion date: July 1, 2025

Study information

• Verified date: May 2023
• Source: Cairo University
• Contact: Ahmed M Rammah, MD
• Phone: 2001005622939
• Email: ahmedrammah2013[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

an intervention study on adult patients with uretero-pelvic junction obstruction (UPJO) due to crossing vessels would be managed either through classic dismembered pyeloplasty or vascular hitch.

Description:

in recent studies, some patients with crossing vessels UPJO could be managed by vascular displacement of these vessels, what is named as vascular hitch or vasculopexy in a way to avoid classic dismembered technique. this newer technique is supposed to provide comparable results to the classic technique but with lesser operative time and shorter hospital stay. in the era of minimally invasive procedures, robotic assisted or laparoscopic vascular hitch could provide many advantages over the classic open technique.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 17
• Est. completion date: July 1, 2025
• Est. primary completion date: June 1, 2025
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• all patients with UPJO above 18 years

• UPJO caused by crossing vessels confirmed by CT angiography

• Symptomatic UPJO

Exclusion Criteria:

• recurrent UPJO after a previous trial of open repair ,

• secondary UPJO after open renal surgery.

• UPJO in non functioning kidney

Related Conditions & MeSH terms

• Hydronephrosis
• Multicystic Dysplastic Kidney
• Ureteral Obstruction
• Ureteropelvic Junction Obstruction

Intervention

Procedure:
• pyeloplasty
repair of the uPJO

Locations

Country	Name	City	State
Egypt	Faculty of Medicine	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	comparing the two techniques regarding the success rate	both techniques are supposed to have similar results	2 years