Predictors of Chronic Kidney Disease Among Type 2 Diabetic Patients in Assiut University Hospitals

Type 2 Diabetes With Renal Manifestations Clinical Trial

— Ckd&dm  

Official title:

Predictors of Chronic Kidney Disease Among Type 2 Diabetic Patients in Assiut University Hospitals

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05847400
• Other study ID #: ckd in tybe 2 dm
• Status: Recruiting
• Start date: March 1, 2024
• Est. completion date: April 1, 2024

Study information

• Verified date: April 2023
• Source: Assiut University
• Contact: Muhammed Al Abualsaud
• Phone: ?+20 106 923 9438?
• Email: Aboalsaud25[@]gmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Predictors of Chronic Kidney Disease among Type 2 Diabetic Patients in Assiut University Hospitals.

Description:

Globally, the total number of people with diabetes is estimated to increase from 415 million (8.8%) in 2015 to 642 million (10.4%) in 2040, with the largest alterations expected to occur in the urban population of low- to middle-income countries (LMICs)1. Of them, type 2 diabetes mellitus (T2DM) accounts for more than 90% of people with diabetes2,3. By 2040, the difference worldwide is projected to broaden, with 477.9 million affected people living in urban areas and 163.9 million in rural areas1. It has been postulated that the burden of diabetes and its complications in the LMICs may be contributed by the economic development and rapid urbanisation via increased caloric intake and the adoption of a sedentary lifestyle2,4,5. More importantly, the most striking demo graphic change to diabetes prevalence in global terms also seems to be related to the growth of the proportion of the elderly population6. Despite rates of diabetes-related complications such as CVDs decreasing significantly in the past two decades, it has not translated nearly as well as kidney complications7. Approximately 10% of deaths in people with T2DM are attributable to kidney failure8. It is well-established that diabetes-related chronic kidney disease (CKD) is the leading cause of end-stage kidney disease (ESKD) in T2DM patients worldwide9,10.

In our study, we aim to identify and classify patients attending diabetic outpatient clinic with both CKD and

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 200
• Est. completion date: April 1, 2024
• Est. primary completion date: March 28, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients with T2DM aged 18 years or older. For patients whom eGFR values < or =60 ml/min/1.73m2.

Patient with type 2 DM and ESRD on regular HD with duration less than 1 year

Exclusion Criteria:

Having kidney transplantation incomplete data on glycemic control. Patients with type 2 DM and ESRD on regular HD with duration more than 1 year. Pregnant woman. Patients with advanced comorbides(cardiac, hepatic,

Related Conditions & MeSH terms

• Diabetic Nephropathies
• Kidney Diseases
• Renal Insufficiency, Chronic
• Type 2 Diabetes With Renal Manifestations

Locations

Country	Name	City	State
Egypt	Assiut	Assiut

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	predictors of CKD among T2DM patients attending Assiut University Hospitals. To classify our patients into stages according to KDIGO guidelines	To identify predictors of CKD among T2DM patients attending Assiut University Hospitals.; To classify our patients into stages according to KDIGO guidelines	3 years
Secondary	the possible risk factors contributing to progessing CKD in T2DM patients.	To identify the possible risk factors contributing to progessing CKD in T2DM patients.	3 years