Clinical Trials Logo

Clinical Trial Summary

1Evaluation of the management methods according to guidelines for cardiac patients admitted to Intensive care in pediatric Assuit university cardiology institute and the effectiveness and outcome of following of these medications comparing them with international advanced centers. Types of shocks in cardiac patients and management of cardiogenic shock needs especial concern.


Clinical Trial Description

Critically ill pediatric patients with cardiac disease such as (cardiogenic Shock, life- threatening arrhythmias, congenital heart diseases with unstable cardiorespiratory status, uncompensated heart failure, after cardiac catheterization and after high risk cardiovascular and intrathoracic procedures) must be admitted to a designated intensive care unit and not discharged untill reversal of the disease process or restoration of the unstable physiologic condition and become hemodynamically stable, cardiac dysrhythmias controlled and there's no need for intravenous inotropic support, vasodilators, and antiarrhythmic drugs or when required, low doses of these medications can be administered safely . Physicians, nurses and other health care providers should perform a regular review of their clinical practice and the activities which carried out relying on established standards and the main purpose of this revision process is to evaluate the efficacy, effectiveness and safety of the provided medical care . Because the number of patients with critical heart diseases is relatively small, there are big knowledge gaps and variation in the methods of management. Presence of a specific Pediatric Cardiac Intensive Care led to correction of this knowledge gap and providing clinicians with Scientific statements and white papers used as a guidance in diagnostic and therapeutic strategies aiming to changing the individual institution-based practices efforts to national standardized protocols which results in a better outcome . Presence of a specific cardiac intensive care unit (CICU) with highly specialized teams with specific knowledge and skills leads to direction of many investigations to provide the highest value care. This has many advantages on the outcome of the admitted patients such as: lower hospital costs, shorter duration of hospital stay and decrease mortality rate . A case of special concern is cardiogenic shock which is an acute state of circulatory failure due to impairment of myocardial contractility and it's the most serious stage of heart failure and a major cause of morbidity and mortality in pediatric cardiac patients, it must be recognized and managed early and any delay in the recognition and management of potential clinical symptoms and signs of compensated shock could lead to a high mortality rate . Recognition of early signs of cardiogenic shock by clinical examination (tachycardia, hypotension, impaired conscious level, fall in oxygen saturation, decreased urine output and respiratory distress) or investigations like as: chest x-ray (cardiomegaly, pulmonary edema), ECG (arrhythmias, conduction disorders, myocardial ischemia),and transthoracic echocardiograms are useful for diagnostic, etiological, therapeutic, and prognostic purposes . Initial management of the cardiogenic shock aiming to restore adequate oxygen delivery to peripheral tissues by oxygen therapy (noninvasive or invasive ventilation) with a saturation objective of >95 % except in cyanotic heart, decrease the circulatory preload by fluid restriction and diuretics, decrease the circulatory afterload by arterial vasodilators, increase the cardiac contractility by inotropes (dopamine, dobutamine and digoxin) and treating curable causes (fluid and electrolyte balance, rhythm, or thromboembolic disorders; pneumothorax, tamponade, infection) . ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05778175
Study type Observational
Source Assiut University
Contact Martina Tharwat Attia salama
Phone 01270735221
Email martinasarwat2020@gmail.com
Status Not yet recruiting
Phase
Start date May 1, 2023
Completion date July 15, 2024

See also
  Status Clinical Trial Phase
Enrolling by invitation NCT05975658 - WIReD: Wireless Interstage Remote Device Study
Completed NCT05546983 - How to Report Postoperative Outcomes After a Paediatric Cardiac Surgery ?
Completed NCT03229538 - STeroids to REduce Systemic Inflammation After Infant Heart Surgery Phase 3
Completed NCT05579964 - The Role of Dexmedetomidine as Myocardial Protector in Pediatric Cardiac Surgery Total Correction of Tetralogy of Fallot Phase 2/Phase 3
Recruiting NCT05128084 - Amotosalen and Platelet Transfusion in Pediatric Heart Surgery
Recruiting NCT04604418 - Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures
Completed NCT05778240 - Adherence to Palivizumab Prophylaxis N/A
Completed NCT04666857 - Family Centred Early Intervention of Infants With Congenital Heart Disease N/A
Terminated NCT03136900 - Impact on the Nitrogen Balance, Autonomy, Safety and Tolerance of Enteral Diets Made of With Nutrilon Without Lactose® Fortified by Concentration Versus by Maltodextrin and Oil Supplementation,After Surgery for Congenital Heart Disease, in Infants. N/A
Recruiting NCT05910320 - Evaluation of an Investigational Wearable Vital Signs Monitoring Device in Healthy Infants N/A
Completed NCT05284500 - Predictive Pre and Peroperative Factors for MODS-2 in Pediatric Cardiac Surgery
Completed NCT04295239 - Non-invasive Monitoring of Cerebral Self-regulation in Perioperative Neonatal Cardiac Surgery N/A
Completed NCT05142046 - Influence of Intraoperative Fluid Balance on the Incidence of Adverse Events in Pediatric Cardiac Surgery
Recruiting NCT04040452 - Continuous vs Intermittent Ketorolac for Pain Control in Peds CV Surgery Phase 4
Recruiting NCT05268094 - Comparison of Methods of Pulmonary Blood Flow Augmentation in Neonates: Shunt Versus Stent (The COMPASS Trial) N/A
Recruiting NCT04315610 - Personalized Mobile App for Parents of Infants With Cardiac Disease N/A
Completed NCT04018079 - Left Ventricular Dysfunction Post-surgical Patent Ductus Arteriosus Ligation in Children: Predictor Factors Analysis
Recruiting NCT05496803 - Impact of Systematic Nursing Guidance on the Psychological Effects of Parents of Children With Cardiac Catheterization. N/A
Recruiting NCT05826769 - To Assess the Efficacy of Early Administration of Energy Enriched and Protein Enriched Formula in Post Cardiac Repair Infants: a Randomized Controlled Trial, Comparative Study N/A
Recruiting NCT04307030 - Study on AI Recognition System Of Heart Sound In Congenital Heart Disease Screening