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Clinical Trial Summary

The purpose of this study is to clarify whether or not a low-dose propofol infusion can effectively prevent postoperative nausea and vomiting (PONV) in patients who have a documented history of PONV and/or motion sickness.


Clinical Trial Description

Propofol is administered as both low dose and as sole anesthetic in patients with history of PONV and/or motion sickness. But efficacy of one dose over the other is not studied. This study plans to clarify if propofol in low dose is as effective as its administration as sole anesthetic in patients with history of PONV and/or motion sickness ;


Study Design


Related Conditions & MeSH terms

  • Nausea
  • Post-operative Nausea and Vomiting
  • Postoperative Nausea and Vomiting
  • Vomiting

NCT number NCT05759481
Study type Interventional
Source Milton S. Hershey Medical Center
Contact Cynthia Reed
Phone 7175310003
Email creed@pennstatehealth.psu.edu
Status Recruiting
Phase Phase 2
Start date February 1, 2024
Completion date April 2026

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Completed NCT00231478 - A Study of Kytril (Granisetron) in the Prevention of Post-Operative Nausea and Vomiting (PONV) in Pediatric Subjects Undergoing Tonsillectomy or Adenotonsillectomy Phase 4