The EASE-IT CT Registry

Transcatheter Aortic Valve Implantation (TAVI) Clinical Trial

Official title: Pre-procedural Assessment of Coronary Artery Disease in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI) - Comparision of Pre-TAVI CTA vs. Pre-TAVI ICA

Status Recruiting

Clinical Trial Summary

ICA is not always required for a pre-TAVI workup of octogenarians and can be substituted by CTA resulting in a streamlined pre-procedural workup of patients without compromising patient safety.

Clinical Trial Description

Patients undergoing TAVI require routine pre-procedural assessment of CAD (coronary artery disease).

ICA (invasive coronary angiography) is the gold standard in patients with high pre-test probability. It is associated, however, with procedural risk, radiation and cost.

CTA (computed tomography angiography) currently has limited use for the evaluation of CAD in pts with severe symptomatic AS (aortic stenosis) - medications required such as beta blockers and nitroglycerine, are frequently not well tolerated by pts.

But as TAVI is increasingly being performed in patients with modest pre-test probabilities for obstructive CAD or a lack of implications thereof (pts. ≥75 yrs), the use of CTA may become more appealing. ;

Related Conditions & MeSH terms

• Coronary Artery Disease
• Transcatheter Aortic Valve Implantation (TAVI)

• NCT number: NCT05750173
• Study type: Observational [Patient Registry]
• Source: Institut für Pharmakologie und Präventive Medizin
• Contact: Claudia Lüske, PhD
• Phone: 044718503324
• Email: claudia.lueske@ippmed.de
• Status: Recruiting
• Start date: September 1, 2023
• Completion date: January 31, 2025