Aneurysmal Subarachnoid Hemorrhage Clinical Trial
Official title:
Machine Learning-based Prediction of Complications, Disability, and Death in Patients With Aneurysmal Subarachnoid Hemorrhage
This study aims to prospectively collect the clinical and radiogical features to investigate the associations between the potential risk factors and secondary complications, adverse long-term functional outcomes, and death in patients with aneurysmal subarachnoid haemorrhage (aSAH).
Status | Recruiting |
Enrollment | 2000 |
Est. completion date | December 30, 2025 |
Est. primary completion date | August 30, 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Subarachnoid hemorrhage was confirmed by CT; - the CTA and DSA examination confirmed is aneurysm rupture caused by subarachnoid hemorrhage; - bleeding after 24 hours of adept 38 blood routine, biochemical function, blood coagulation function and craniocerebral CT; - DCI was observed during 3 to 14 days after surgery; - aneurysm clip by surgery or endovascular embolization. Exclusion Criteria: - Aneurysm rupture bleeding time more than 24 hours; - by CTA and DSA examination found no intracranial aneurysm; - Traumatic subarachnoid hemorrhage; - the image data and check blood information is not complete; - long-term anticoagulant drugs such as aspirin, wave dimensions; - admitted to hospital with infectious diseases; - merging other intracranial vascular malformation. |
Country | Name | City | State |
---|---|---|---|
China | The Second Affiliated Hospital of Nanchang University | Nanchang | Jiangxi |
Lead Sponsor | Collaborator |
---|---|
Second Affiliated Hospital of Nanchang University | Renmin Hospital of Wuhan University, Southwest Hospital, China, Zhejiang University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | modified Rankin Scale for evaluating the prognosis | A score greater than 3 indicates a poor prognosis, while a score less than 3 indicates a good prognosis | 12 months | |
Primary | Delayed cerebral ischemia | A state of transition in cerebral ischemia | 30 days | |
Secondary | Rebleeding | Intracerebral aneurysm rerupture | 30 days | |
Secondary | Hydrocephalus | Obstruction of cerebrospinal fluid circulation leads to ventricle dilation | 30 days | |
Secondary | Clearing rate of subarachnoid hemorrhage | BrainHemoAI software used to quantify subarachnoid hemorrhage volume from admission CT scans to dischage CT scans. | 14 days |
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