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Prognostic Model of Rituximab in the Treatment of MN

Idiopathic Membranous Nephropathy Clinical Trial

Official title:
Development and Validation of a Prognostic Model for Idiopathic Membranous Nephropathy Treated With Rituximab

Clinical Trial Summary

The goal of this observational study is to explore the factors that can predict the prognosis difference in patients with idiopathic membranous nephropathy (IMN) under the treatment of rituximab. The main questions it aims to answer are: - to explore the factors that can predict the prognosis difference in patients with IMN under the treatment of rituximab - to establish a clinical prediction model and verify it to provide a reference for the early Participants will receive standard the treatment of rituximab treatment and will then be divided into remission and non remission groups based on the treatment effect after the standard treatment cycle. Blood, urine, and fecal samples were collected from patients to explore possible factors influencing treatment efficacy. Researchers will compare [remission group and non-remission group] to see if the gut microbiota and its metabolites are factors that influence the efficacy of treatment.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05667909
Study type Observational
Source Qianfoshan Hospital
Contact
Status Not yet recruiting
Phase
Start date June 2023
Completion date December 2023
View Details
See also
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