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Clinical Trial Summary

Healthy volunteers (n = 28) were recruited from the workplace (14 male, 14 female; age range 20-50 years). Ethical approval, which included informed consent, was from Cardiff University, Schools of Medicine and Dentistry Research Ethics Committee (SMREC16/02). Following a 2-week period free from non-steroidal anti-inflammatory drugs (NSAIDs), peripheral blood was obtained and platelets isolated. Participants were commenced on aspirin 75 mg once daily for seven days and then provided a repeat blood sample. Following a 2-month period, participants were invited to repeat samples pre- and post-aspirin, and again a third time 2 months later.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms

  • Platelet Dysfunction Due to Aspirin

NCT number NCT05604118
Study type Interventional
Source Cardiff University
Contact
Status Completed
Phase N/A
Start date August 1, 2016
Completion date June 1, 2022

See also
  Status Clinical Trial Phase
Recruiting NCT03255928 - Dynamics of Platelet Activation in Patients With Ventricular Assist Device (VAD)
Completed NCT01361620 - Genotypic and Phenotypic Correlates of Resistance to Aspirin N/A