Clinical Trials Logo

Clinical Trial Summary

This is a phase Ib/II, open label clinical study to evaluate the safety, tolerability and antitumor activities of IN10018 in combination with standard chemotherapy in subjects with high-grade serous ovarian cancer (including fallopian tube cancer and primary peritoneum cancer, collectively defined as ovarian cancer).


Clinical Trial Description

Study will evaluate IN10018 in combination with pegylated liposomal doxorubicin (PLD) in subjects with platinum-resistant recurrent ovarian cancer. All the subjects will receive combination therapy until documented progressive disease or unacceptable toxicity. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05551507
Study type Interventional
Source InxMed (Shanghai) Co., Ltd.
Contact Jack Zhang
Phone 86-18611511983
Email jack.zhang@inxmed.com
Status Recruiting
Phase Phase 1/Phase 2
Start date July 27, 2020
Completion date December 2024

See also
  Status Clinical Trial Phase
Recruiting NCT05494580 - Pamiparib Plus Surufatinib in Patients With Platinum-resistant Ovarian Cancer Phase 1/Phase 2
Recruiting NCT05756907 - Combination of SON-1010 (IL12-FHAB) and Atezolizumab in Patients With Platinum-resistant Ovarian Cancer Phase 1/Phase 2
Recruiting NCT04787289 - A Comparison of 2 Standard Doses of Bevacizumab in Combination With Chemotherapy in Epithelial Ovarian Cancer Phase 2
Completed NCT04504916 - A Study of Zilovertamab Vedotin (MK-2140) (VLS-101) in Participants With Solid Tumors (MK-2140-002) Phase 2
Recruiting NCT06090266 - A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents Phase 1/Phase 2
Active, not recruiting NCT05979298 - Efficacy of Plasmid Elenagen in Combination With Gemcitabine in Patients With Platinum-resistant Ovarian Cancer Phase 2
Recruiting NCT04376073 - Anlotinib and Niraparib Dual Therapy Evaluation in Platinum-resistant Recurrent Ovarian Cancer Phase 2
Not yet recruiting NCT06321484 - Intraperitoneal Cytokine-Induced Memory Like (CIML) Natural Killer (NK) Cells in Recurrent Ovarian Cancer Phase 1
Recruiting NCT05271318 - Oncolytic Adenovirus TILT-123 With Pembrolizumab as Treatment for Ovarian Cancer Phase 1
Terminated NCT02575807 - Safety and Efficacy of CRS-207 With Epacadostat in Platinum Resistant Ovarian, Fallopian or Peritoneal Cancer Phase 1/Phase 2
Recruiting NCT06242470 - A Study of MGC026 in Participants With Advanced Solid Tumors Phase 1
Recruiting NCT05310344 - Albumin-bound Paclitaxel and Bevacizumab for Platinum-resistant Recurrent Ovarian Cancer Phase 2
Withdrawn NCT05736952 - Oral Topotecan Combined With Anlotinib in Patients With Platinum-resistant Recurrent Ovarian Cancer Phase 2
Active, not recruiting NCT04374630 - Study With Afuresertib and Paclitaxel in Platinum Resistant Ovarian Phase 2
Active, not recruiting NCT03949283 - Cancer Stem Cell Assay Directed Chemotherapy in Recurrent Platinum Resistant Ovarian Cancer Phase 3
Not yet recruiting NCT06315491 - A Study of CBX 12 in Subjects With Platinum Resistant or Refractory Ovarian Cancer Phase 2
Recruiting NCT05870748 - REFRaME-O1: A Study to Investigate the Efficacy and Safety of Luveltamab Tazevibulin Versus Investigator's Choice (IC) Chemotherapy in Women With Ovarian Cancer (Including Fallopian Tube or Primary Peritoneal Cancers) Expressing FOLR1 Phase 2/Phase 3
Recruiting NCT05198804 - A Study of ZN-c3 and Niraparib in Subjects With Platinum-Resistant Ovarian Cancer Phase 1/Phase 2
Terminated NCT04718376 - A Study of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Relapsed Ovarian Cancer Phase 1
Recruiting NCT05081609 - A Study to Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or Chemotherapy or TransCon TLR7/8 Agonist in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies Phase 1/Phase 2