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NCT05388955 Clinical Trial

Risk Assessment Tool for Graft Survival in Pediatric Kidney Transplantation

Kidney Transplant Failure and Rejection Clinical Trial

Official title:
A Pre-transplantation Risk Assessment Tool for Graft Survival After Pediatric Kidney Transplantation Based on 1425 Dutch Transplantations

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05388955
Other study ID # Riskcalculator.Pediatric.ntx
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 1966
Est. completion date January 1, 2022

Study information
Verified date May 2022
Source Radboud University Medical Center
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Registry study in which data of all pediatric kidney recipients in the Netherlands (registered in the Nederlandse Orgaan Transplantatie Registry) are studied to develop a risk calculator for graft loss.

Description:

The pre-transplantation parameters of all recipients are used to do a multivariable regression analysis. The B-coefficients of this analysis will be used to develop a risk calculator that predicts graft survival after transplantation per year of transplantation.

Recruitment information / eligibility
Status Completed
Enrollment 1425
Est. completion date January 1, 2022
Est. primary completion date January 1, 2022
Accepts healthy volunteers No
Gender All
Age group 0 Years to 18 Years
Eligibility Inclusion Criteria: Pediatric kidney recipients - transplantation in the Netherlands - signed informed consent Exclusion Criteria: - combined transplantation (pancreas-kidney of liver-kidney transplantation) - No informed consent

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• None, transplantation recipients
None, observational

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Radboud University Medical Center

Outcome
Type Measure Description Time frame Safety issue
Primary Graft survival Functioning graft of death with functioning graft. Survival graph: Percentage recipients with a functioning graft over time Up to 50 years after transplantation
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