Clinical Trials Logo

Clinical Trial Summary

This study aimed to evaluate the safety and feasibility of neoadjuvant tislelizumab combined with chemoradiotherapy in patients with resectable esophageal squamous cell cancer. The tumor microenvironment and circulating immunological biomarkers in these patients were further evaluated to explore the factors affecting the efficacy of neoadjuvant therapy for esophageal cancer. This study will provide valuable information for further prospective clinical trials of neoadjuvant anti-PD-1 and other immunotherapy in esophageal cancer patients.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05323890
Study type Interventional
Source Shandong Cancer Hospital and Institute
Contact Xue Meng, Ph.D, M.D
Phone 17653115602
Email mengxuesdzl@163.com
Status Recruiting
Phase Phase 2
Start date April 20, 2022
Completion date October 20, 2024

See also
  Status Clinical Trial Phase
Recruiting NCT03732508 - SHR-1316 in Combination With Chemotherapy in Patients With Esophageal Squamous Cell Cancer Phase 2
Not yet recruiting NCT04797507 - SHR-1210 in Combination With Anlotinib in Patients With Advanced or Metastatic Esophageal Squamous Cell Cancer Phase 2
Recruiting NCT04437212 - Neoadjuvant Chemoradiotherapy Combined With Perioperative Toripalimab in Locally Advanced Esophageal Cancer Phase 2