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Clinical Utility of the Addition of a SNP-based NIPT Zygosity Determination in Twin Pregnancy Management. — ZTWINS  

Pregnancy Complications Clinical Trial

Official title:
Clinical Utility of the Addition of a SNP-based NIPT Zygosity Determination in Twin Pregnancy Management.

Clinical Trial Summary

The ZTWINS registry study is an observational, prospective, multi-center study observing women carrying a twin pregnancy who receive snp-based non-invasive prenatal screening and zygosity assessment as part of their medical care.

Clinical Trial Description

This observational data collection study will include subjects with ultrasound-confirmed twin pregnancy and planned NIPS zygosity assessment as a part of their clinical care. Initial chorionicity assessment and, when available, planned twin pregnancy management (e.g., frequency of prenatal ultrasounds, maternal fetal medicine (MFM) referral etc) will be recorded in the study database. Following zygosity results being returned through clinical care NIPS, updated chorionicity & amnionicity will again be recorded in the study database. Other clinical data in the medical record as part of clinical care, including monochorionic twin pregnancy complications (TTTS, FTC referral, etc), placenta pathology findings, and delivery and neonatal outcomes will also be recorded in the study database. There will be no study blood sample collection or other study procedures performed as part of this study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05312814
Study type Observational
Source Natera, Inc.
Contact
Status Completed
Phase
Start date October 1, 2021
Completion date May 15, 2023
View Details
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