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Clinical Trial Summary

Primary Objective: Part A - To quantify deficits in cognitive functioning in adolescents with moderate-to-severe AD, using the Conners' Continuous Performance Test 3rd Edition (CPT-3) d' T-score - To determine the entry criterion (CPT-3 d' score) for Part B Primary Objective: Part B - To measure changes in cognitive functioning in adolescents with moderate-to-severe AD treated with dupilumab Secondary Objectives - To evaluate the relationship of cognitive and sensory functioning with severity of AD in adolescent AD patients - To evaluate the relationship between changes in AD severity and changes in cognitive and sensory functioning scores following treatment with dupilumab (Part B only).


Clinical Trial Description

Per protocol Study Stop Criteria, study has concluded with Part A. Part B was not initiated and no data were collected. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05203380
Study type Observational
Source Regeneron Pharmaceuticals
Contact
Status Completed
Phase
Start date January 27, 2022
Completion date March 10, 2023

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