Clinical Trials Logo
  1. Home
  2. Other
  3. NCT05184023

The Effect of PEMF for Patients With Quadriceps Muscle Weakness After ACLR

Anterior Cruciate Ligament Injuries Clinical Trial

Official title:
A Double-Blinded, Randomized-Controlled-Trial to Investigate the Effect of Pulsed Electromagnetic Field (PEMF) for Patients With Quadriceps Weakness After Anterior Cruciate Ligament Reconstruction (ACLR)

Clinical Trial Summary

In Hong Kong, over 3000 Anterior Cruciate Ligament Reconstructions (ACLR) are performed each year in order to restore knee function after an ACL injury. The ultimate goal of ACLR is to fulfil the return-to-play (RTP) criteria. Despite successful surgery and a demanding rehabilitation process, some athletes still fail to comply to RTP. For those who achieve RTP, 23% of those who return to their sports would suffer a second ACL injury. Quadriceps muscle strength is one of the key determinants for a patient's successful return- to-play after ACLR. Quadriceps muscle atrophy can persist beyond the completion of the rehabilitation program in almost half the patients and the reason behind this is still unknown. Therefore, there is need to find a more effective way to increase quadriceps strength. There are emerging evidences showing that pulsed electromagnetic field (PEMF) can modulate mitochondrial activities for muscle gain. PEMF exposure on top of regular exercise training may promote muscle regeneration and tissue healing. This study aims to conduct a double-blinded, randomized controlled trial to investigate the effects of PEMF treatment during the late postoperative period on quadriceps muscle strength in ACL injured patient. Muscle endurance could only be investigated in late postoperative period. The investigators hypothesize that PEMF treatment is effective to reduce muscle weakness and promote gain in quadriceps muscle strength in ACLR patients. Based on the aim of this study, adult patients (aged 18-30) with a unilateral ACL injury, total quadriceps muscle volume is equal or morn than 7% deficit on involved leg compared with uninvolved leg, sporting injury with a Tegner score of 7+, both knees without a history of injury/prior surgery will be recruited. To estimate the improvement of patients, Isokinetic muscle assessment, ultrasound imaging and MRI for quadriceps muscle thickness, self-reported outcomes with questionnaires, KT-1000 for knee laxity and biomechanical analysis, Xtreme CT for Bone mineral density will be performed. To investigate the mechanism of PEMF therapy on increasing quadriceps strength, samples of blood serum will be draw before and after intervention.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05184023
Study type Interventional
Source Chinese University of Hong Kong
Contact
Status Active, not recruiting
Phase N/A
Start date September 1, 2021
Completion date September 1, 2025
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT04062578 - Effects Provided by a Physiotherapy Treatment Preventing Lower Extremity Injuries in Female Football Players N/A
Recruiting NCT05461326 - Quadriceps Tendon Versus Bone Patellar Tendon Bone Autograft ACL Reconstruction RCT N/A
Completed NCT05109871 - Reliability and Validity of Inline Dynamometry Study for Measuring Knee Extensor Torque N/A
Completed NCT05504018 - Clinical and Radiological Evaluation of ACL Reconstruction Results N/A
Recruiting NCT06185231 - Investigation of the Effects of Vibration Therapy on Pain, Functionality, and Proprioception After ACL Injury N/A
Recruiting NCT03968913 - Biologic Therapy to Prevent Osteoarthritis After ACL Injury Early Phase 1
Completed NCT04408690 - Feasibility of a RCT That Compares Immediate Versus Optional Delayed Surgical Repair After ACL Injury Phase 3
Recruiting NCT06222814 - Evaluation of the Results of Two Different Methods in Management of Antero-lateral Instability of the Knee N/A
Recruiting NCT05614297 - Agreement Between Rolimeter and Lachmeter in Patients With ACL Injury
Completed NCT04906538 - Objective Results of Anterior Cruciate Ligament Reconstruction With and Without Internal Suture Augmentation Technique Phase 2/Phase 3
Completed NCT05014009 - The Influence of Neuromuscular Training on Whole-body Movement Strategies and Knee Mechanics During Change-of-direction Tasks in Sports Science Students N/A
Not yet recruiting NCT06083818 - Anterior Cruciate Ligament Injury Prevention Protocol in Female Football Players With Dynamic Knee Valgus N/A
Recruiting NCT05584020 - Arthroscopic Anterior Cruciate Ligament Repair Versus Reconstruction for Acute Anterior Cruciate Ligament Injury N/A
Completed NCT04580290 - Jewel ACL Post Market Clinical Follow Up Study
Recruiting NCT04888052 - Prolonged Preoperative Rehabilitation in ACL Rupture. N/A
Not yet recruiting NCT05580133 - All-Inside Single-Bundle for Anterior Cruciate Ligament Reconstruction With Full Thickness of the Peroneus Longus Tendon Compared to the Six-strand-hamstring Autograft (ACL)
Recruiting NCT04162613 - Can Sensorimotor Function Predict Graft Rupture After ACL Reconstruction
Not yet recruiting NCT05619393 - Comparison of Kinematic Movements Between ACL Deficiency With ACL Reconstruction and Healthy People N/A
Recruiting NCT06201442 - Post-Traumatic Knee Osteoarthritis Following Anterior Cruciate Ligament Reconstruction
Not yet recruiting NCT05068297 - The Impact of Germanium-Embedded Knee Brace on Patient Recovery After ACL Reconstruction N/A