Optical Coherence Tomography Angiography and Pseudophakic Cystoid Edema

Pseudophakic Cystoid Macular Edema Clinical Trial

Official title:

Peripapillary Vascular Density in the Pathogenesis of Pseudophakic Cystoid Edema

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05117411
• Other study ID #: 09/21
• Status: Completed
• Start date: January 1, 2016
• Est. completion date: December 30, 2020

Study information

• Verified date: November 2021
• Source: Federico II University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study evaluates the retinal vascular features in macula and papillary regions in patients affected by pseudophakic cystoid edema using optical coherence tomography angiography

Description:

Pseudophakic cystoid edema represents one of the most common causes of poor visual outcome following cataratta surgery.

It is still source of debate the pathogenesis of Pseudophakic cystoid edema. Optical coherence tomography angiography represents a novel and non-invasive diagnostic technique that allows a detailed analysis of retinal vascular features. The study evaluates retrospectively the changes in optical coherence tomography angiography parameters at baseline and after three monthly after surgery.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 25
• Est. completion date: December 30, 2020
• Est. primary completion date: December 15, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 60 Years to 80 Years

Eligibility

Inclusion Criteria:

• age older than 60 years

• diagnosis of pseudophakic cystoid macular oedema

• treatment-naïve for pseudophakic cystoid macular oedema

• absence of other ocular diseases, responsible for macular edema (retinal vein occlusion, diabetic retinopathy, age-related macular degeneration)

Exclusion Criteria:

• age younger than 60 years

• No diagnosis of pseudophakic cystoid macular oedema

• previous treatment for pseudophakic cystoid macular oedema

• presence of other ocular diseases, responsible for macular edema (retinal vein occlusion, diabetic retinopathy, age-related macular degeneration)

Related Conditions & MeSH terms

• Edema
• Macular Edema
• Pseudophakic Cystoid Macular Edema

Intervention

Diagnostic Test:
• OCTA and pseudophakin cystoid edema
Patients underwent OCT angiografia after cataract surgery

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Federico II University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	OCTA and pseudophakic cystoid macular oedema	The parameters analyzed by OCTA three months after surgery are: Vessel density (%) of superficial capillary plexus, deep capillary plexus, coriocapillary plexus in macular region Vessel density (%) of radial peripapillary capillary plexus in papilllary region	3 months