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Clinical Trial Summary

Adequate bowel cleansing is a critical component in the care of hospitalized patients undergoing colonoscopy. However, inpatient status is a well-established risk factor for inadequate bowel preparation. However, few strategies have been rigorously shown to reduce the risk of inadequate bowel preparation. Moreover, inadequate bowel preparation is frequently related to the poor tolerability of high volumes of bowel preparation in the medically complex and comorbid hospitalized population. Low volume bowel preparations have been developed that have been shown to be noninferior compared to high volume bowel preparation with regards to adequacy of bowel preparation but with improved tolerability. However, the use of low volume bowel preparations for colonoscopies have largely been evaluated in the outpatient setting. In this study, we plan to compare rates of adequate bowel preparation and tolerability of a low volume bowel preparation, MoviPrep, compared to standard high volume bowel preparation, GoLYTELY, in hospitalized patients undergoing colonoscopy. This study promises to highlight low volume bowel preparation as a viable and better tolerated alternative to high volume bowel preparation in hospitalized patients which may ultimately decrease delays in inpatient endoscopy as well as hospital length of stay.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms

  • Bowel Preparation Before Colonoscopy

NCT number NCT05054036
Study type Interventional
Source Yale University
Contact Darrick K Li, MD, PhD
Phone 203-285-4506
Email darrick.li@yale.edu
Status Recruiting
Phase Phase 4
Start date January 12, 2022
Completion date August 1, 2024

See also
  Status Clinical Trial Phase
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Recruiting NCT05498714 - Improved Bowel Cleansing Method for Colonoscopy Based on High Risk Population of Bowel Preparation N/A
Completed NCT01745835 - Comparison Between 2L Coolprep® and Combination of 1L Coolprep® and Bisacodyl as Bowel Preparation Phase 3
Completed NCT02910440 - A Safety and Efficacy Study of DCL-101 Compared to GoLYTELY Phase 2
Completed NCT04582942 - Improved Bowel Preparation Method for Colonoscopy Based on Different Risk Stratification N/A
Recruiting NCT03106922 - A Trial to Evaluate the Efficacy and Safety of PMF104 Compared to a Conventional PEG-electrolyte Solution in Children Phase 3