Effect of Functional Endoscopic Sinus Surgery On Eustachian Tube Function in Patients With Nasal Polypi

Functional Endoscopic Sinus Surgery Clinical Trial

Official title: Effect of Functional Endoscopic Sinus Surgery On Eustachian Tube Function in Patients With Nasal Polypi

Status Not yet recruiting

Clinical Trial Summary

This study is conducted to :

Correlate the incidence of ETD with nasal polypi. To evaluate the effects of functional endoscopic sinus surgery on eustachian tube function in patients with nasal polypi

Clinical Trial Description

Eustachian tube dysfunction (ETD) is a frequently applied diagnosis, used when abnormal ET function is believed to underlie any of a wide range of symptoms or middle ear (ME) abnormalities. Two distinct forms of the disorder are recognised, representing different ends of the spectrum of ET function: 1)obstructive ETD (OETD), in which tubal opening or patency is reduced, and 2) patulous ETD (PETD), in which the ET is too open. It has been suggested that some patients with OETD have either predominantly active dysfunction (failure of muscle-controlled opening), or passive dysfunction (failure of pressure-related opening).

There are several explanations to account for the ET dysfunction associated with nasal diseases:

• Mechanical obstruction of ET orifice may occur due to nasal mass.

• Increased secretions from seromucous glands in the pharyngeal portion of ET may accumulate and block the tube.

• Lymphatic stasis due to edema of the submucosa of the tube resulting in compromise of the lumen may produce ET dysfunction.

• Further increase in hydrostatic pressure result in the accumulation of ME fluid by transudative process.

• Tubal dysfunction may be related to deficiency of surfactant that is thought to facilitate tubal opening. It has been postulated that this material is inactivated by inflammation.

ETD symptoms will decrease post-endoscopic sinus surgery to a level comparable with a non-CRS population The use of the ETDQ-7 has the potential to enhance clinical care by highlighting the impact of ETD as well as guiding and evaluating appropriate management. Further prospective testing of ;

Related Conditions & MeSH terms

• Functional Endoscopic Sinus Surgery

• NCT number: NCT05053906
• Study type: Observational
• Source: Assiut University
• Contact: Safia Sh Abd-Ellattef, 3
• Phone: 01033111172
• Email: safeyasaleh21@gmail.com
• Status: Not yet recruiting
• Start date: November 1, 2021
• Completion date: May 1, 2023